374 citations · 1.7k across the 55 of their papers we have counts for
4 papers · 1 filter
How kinesin waits for ATP affects the nucleotide and load dependence of the stepping kinetics
Ryota Takaki, Mauro L. Mugnai, Yonathan Goldtzvik +1
Dimeric molecular motors walk on polar tracks by binding and hydrolyzing one ATP per step. Despite tremendous progress, the waiting state for ATP binding in the well-studied kinesi…
Dual Role of Cell-Cell Adhesion In Tumor Suppression and Proliferation Due to Collective Mechanosensing
Abdul Malmi-Kakkada, Xin Li, Sumit Sinha +1
It is known that mechanical interactions couple a cell to its neighbors, enabling a feedback loop to regulate tissue growth. However, the interplay between cell-cell adhesion stren…
Conformational Heterogeneity in Human Interphase Chromosome Organization Reconciles the FISH and Hi-C Paradox
Guang Shi, D. Thirumalai
Hi-C experiments are used to infer the contact probabilities between loci separated by varying genome lengths. Contact probability should decrease as the spatial distance between t…
Generalized Rayleigh-Plesset Theory for Cell Size Maintenance in Viruses and Bacteria
Abdul Malmi-Kakkada, D. Thirumalai
The envelopes covering bacterial cytoplasm possess remarkable elastic properties. They are rigid enough to resist large pressures while being flexible enough to adapt to growth und…