73 citations · 208 across the 8 of their papers we have counts for
8 papers
Epigenetic state encodes locus-specific chromatin mechanics
Guang Shi, D. Thirumalai
Chromatin is repeatedly deformed in vivo during transcription, nuclear remodeling, and confined migration - yet how mechanical response varies from locus to locus, and how it relat…
Static Three-Dimensional Structures Determine Fast Dynamics Between Distal Loci Pairs in Interphase Chromosomes
Guang Shi, Sucheol Shin, D. Thirumalai
Live-cell imaging experiments have shown that the distal dynamics between enhancers and promoters are unexpectedly rapid and incompatible with standard polymer models. The discorda…
Minimal Models for RNA Simulations
D. Thirumalai, Naoto Hori, Hung T. Nguyen
The increasing importance of RNA as a prime player in biology can hardly be overstated. Problems in RNA, such as folding and RNA-RNA interactions that drive phase separation, requi…
Organization and Dynamics of Chromosomes
D. Thirumalai, Guang Shi, Sucheol Shin +1
How long threadlike eukaryotic chromosomes fit tidily in the small volume of the nucleus without significant entanglement is just beginning to be understood, thanks to major advanc…
Transcription-induced active forces suppress chromatin motion
Sucheol Shin, Guang Shi, Hyun Woo Cho +1
The organization of interphase chromosomes in a number of species is starting to emerge thanks to advances in a variety of experimental techniques. However, much less is known abou…
Ion Condensation onto Ribozyme is Site-Specific and Fold-Dependent
Naoto Hori, Natalia A. Denesyuk, D. Thirumalai
The highly charged RNA molecules, with each phosphate carrying a single negative charge, cannot fold into well-defined architectures with tertiary interactions, in the absence of i…