374 citations · 1.7k across the 55 of their papers we have counts for
55 papers
From Effective Interactions Extracted Using Hi-C Data to Chromosome Structures in Conventional and Inverted Nuclei
Sucheol Shin, Guang Shi, D. Thirumalai
Contact probabilities between loci, separated by arbitrary genomic distance, for a number of cell types have been reported using genome-wide chromosome conformation capture (Hi-C)…
Conformational Fluctuations and Phases in Fused in Sarcoma (FUS) Low-Complexity Domain
D. Thirumalai, Abhinaw Kumar, Debayan Chakraborty +2
The well known phenomenon of phase separation in synthetic polymers and proteins has become a major topic in biophysics because it has been invoked as a mechanism of compartment fo…
Watching ion-driven kinetics of ribozyme folding and misfolding caused by energetic and topological frustration one molecule at a time
Naoto Hori, D. Thirumalai
Folding of ribozymes into well-defined tertiary structures usually requires divalent cations. How Mg ions direct the folding kinetics has been a long-standing unsolved probl…
Topological transitions, turbulent-like motion and long-time-tails driven by cell division in biological tissues
Xin Li, Sumit Sinha, T. R. Kirkpatrick +1
The complex spatiotemporal flow patterns in living tissues, driven by active forces, have many of the characteristics associated with inertial turbulence even though the Reynolds n…
Friends in need: how chaperonins recognize and remodel proteins that require folding assistance
George Stan, George H. Lorimer, D. Thirumalai
Chaperonins are biological nanomachines that help newly translated proteins to fold by rescuing them from kinetically trapped misfolded states. Protein folding assistance by the ch…
Free volume theory explains the unusual behavior of viscosity in a non-confluent tissue during morphogenesis
Rajsekhar Das, Sumit Sinha, Xin Li +2
A recent experiment on zebrafish blastoderm morphogenesis showed that the viscosity (η) of a non-confluent embryonic tissue grows sharply until a critical cell packing fraction (ϕS…