374 citations · 1.7k across the 55 of their papers we have counts for
3 papers · 1 filter
Share, but unequally: A plausible mechanism for emergence and maintenance of intratumor heterogeneity
Xin Li, D. Thirumalai
Intratumor heterogeneity (ITH), referring to coexistence of different cell subpopulations in a single tumor, has been a major puzzle in cancer research for almost half a century. T…
Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover
Naoto Hori, Natalia A. Denesyuk, D. Thirumalai
We investigated frictional effects on the folding rates of a human telomerase hairpin (hTR HP) and H-type pseudoknot from the Beet Western Yellow Virus (BWYV PK) using simulations…
Charge fluctuation effects on the shape of flexible polyampholytes with applications to Intrinsically disordered proteins
Himadri S. Samanta, Debayan Chakraborty, D. Thirumalai
Random polyampholytes (PAs) contain positively and negatively charged monomers that are distributed randomly along the polymer chain. The interaction between charges is assumed to…