2.5k citations
- Harvard UniversityUS38 papers
- Institute for Advanced StudyUS13 papers
- Centre National de la Recherche ScientifiqueFR6 papers
- Laboratoire de Physique ThéoriqueFR5 papers
- University of PennsylvaniaUS4 papers
- Brigham and Women's HospitalUS3 papers
- Princeton UniversityUS3 papers
- University of CambridgeGB3 papers
- Columbia UniversityUS2 papers
- Howard Hughes Medical InstituteUS2 papers
- Laboratoire de Physique de l'Ecole Normale SupérieureFR2 papers
- Northeastern UniversityUS2 papers
4 papers · 1 filter
Statistical inference of the generation probability of T-cell receptors from sequence repertoires
Anand Murugan, Thierry Mora, Aleksandra M. Walczak +1
Stochastic rearrangement of germline DNA by VDJ recombination is at the origin of immune system diversity. This process is implemented via a series of stochastic molecular events i…
Genetic Diversity and the Structure of Genealogies in Rapidly Adapting Populations
Michael M. Desai, Aleksandra M. Walczak, Daniel S. Fisher
Positive selection distorts the structure of genealogies and hence alters patterns of genetic variation within a population. Most analyses of these distortions focus on the signatu…
Selective sweeps in growing microbial colonies
Kirill S Korolev, Melanie J I Müller, Nilay Karahan +3
Evolutionary experiments with microbes are a powerful tool to study mutations and natural selection. These experiments, however, are often limited to the well-mixed environments of…
A General Framework for Modeling and Online Optimization of Stochastic Hybrid Systems
Ali Kebarighotbi, Christos G. Cassandras
We extend the definition of a Stochastic Hybrid Automaton (SHA) to overcome limitations that make it difficult to use for on-line control. Since guard sets do not specify the exact…