124 citations · 278 across the 20 of their papers we have counts for
20 papers
Social network structure and the spread of complex contagions from a population genetics perspective
Julian Kates-Harbeck, Michael M. Desai
Ideas, behaviors, and opinions spread through social networks. If the probability of spreading to a new individual is a non-linear function of the fraction of the individuals' affe…
The competition between simple and complex evolutionary trajectories in asexual populations
Ian E. Ochs, Michael M. Desai
On rugged fitness landscapes where sign epistasis is common, adaptation can often involve either individually beneficial "uphill" mutations or more complex mutational trajectories…
Pleiotropic consequences of adaptation across gradations of environmental stress in budding yeast
Elizabeth R. Jerison, Sergey Kryazhimskiy, Michael M. Desai
Adaptation to one environment often results in fitness gains and losses in other conditions. To characterize how these consequences of adaptation depend on the physical similarity…
The impact of macroscopic epistasis on long-term evolutionary dynamics
Benjamin H. Good, Michael M. Desai
Genetic interactions can strongly influence the fitness effects of individual mutations, yet the impact of these epistatic interactions on evolutionary dynamics remains poorly unde…
Deleterious passengers in adapting populations
Benjamin H Good, Michael M Desai
Most new mutations are deleterious and are eventually eliminated by natural selection. But in an adapting population, the rapid amplification of beneficial mutations can hinder the…
The Fates of Mutant Lineages and the Distribution of Fitness Effects of Beneficial Mutations in Laboratory Budding Yeast Populations
Evgeni M. Frenkel, Benjamin H. Good, Michael M. Desai
The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting microbial populations, this process is particularly hard to predict because lineages…