811 citations · 7.3k across the 89 of their papers we have counts for
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Non-equilibrium dynamics of adaptation in sensory systems
Daniele Conti, Thierry Mora
Adaptation is used by biological sensory systems to respond to a wide range of environmental signals, by adapting their response properties to the statistics of the stimulus in ord…
Deep generative selection models of T and B cell receptor repertoires with soNNia
Giulio Isacchini, Aleksandra M Walczak, Thierry Mora +1
Subclasses of lymphocytes carry different functional roles to work together to produce an immune response and lasting immunity. Additionally to these functional roles, T and B-cell…
Learning the heterogeneous hypermutation landscape of immunoglobulins from high-throughput repertoire data
Natanael Spisak, Aleksandra M. Walczak, Thierry Mora
Somatic hypermutations of immunoglobulin (Ig) genes occuring during affinity maturation drive B-cell receptors' ability to evolve strong binding to their antigenic targets. The lan…
Immune Fingerprinting through Repertoire Similarity
Thomas Dupic, Meriem Bensouda Koraichi, Anastasia Minervina +3
Immune repertoires provide a unique fingerprint reflecting the immune history of individuals, with potential applications in precision medicine. However, the question of how person…
A new inference approach for training shallow and deep generalized linear models of noisy interacting neurons
Gabriel Mahuas, Giulio Isacchini, Olivier Marre +2
Generalized linear models are one of the most efficient paradigms for predicting the correlated stochastic activity of neuronal networks in response to external stimuli, with appli…
Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection
Anastasia A. Minervina, Ekaterina A. Komech, Aleksei Titov +10
COVID-19 is a global pandemic caused by the SARS-CoV-2 coronavirus. T cells play a key role in the adaptive antiviral immune response by killing infected cells and facilitating the…