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Dynamical criticality in the collective activity of a population of retinal neurons
Thierry Mora, Stéphane Deny, Olivier Marre
Recent experimental results based on multi-electrode and imaging techniques have reinvigorated the idea that large neural networks operate near a critical point, between order and…
High accuracy decoding of dynamical motion from a large retinal population
Olivier Marre, Vicente Botella-Soler, Kristina D. Simmons +3
Motion tracking is a challenge the visual system has to solve by reading out the retinal population. Here we recorded a large population of ganglion cells in a dense patch of salam…
Capturing coevolutionary signals in repeat proteins
Rocío Espada, R. Gonzalo Parra, Thierry Mora +2
The analysis of correlations of amino acid occurrences in globular proteins has led to the development of statistical tools that can identify native contacts -- portions of the cha…
How a well-adapted immune system is organized
Andreas Mayer, Vijay Balasubramanian, Thierry Mora +1
The repertoire of lymphocyte receptors in the adaptive immune system protects organisms from diverse pathogens. A well-adapted repertoire should be tuned to the pathogenic environm…
Thermodynamics for a network of neurons: Signatures of criticality
Gasper Tkacik, Thierry Mora, Olivier Marre +3
The activity of a neural network is defined by patterns of spiking and silence from the individual neurons. Because spikes are (relatively) sparse, patterns of activity with increa…
Thermodynamics of statistical inference by cells
Alex H. Lang, Charles K. Fisher, Thierry Mora +1
The deep connection between thermodynamics, computation, and information is now well established both theoretically and experimentally. Here, we extend these ideas to show that the…