811 citations · 7.3k across the 89 of their papers we have counts for
9 papers · 1 filter
Physical epistatic landscape of antibody binding affinity
Rhys M. Adams, Justin B. Kinney, Aleksandra M. Walczak +1
Affinity maturation produces antibodies that bind antigens with high specificity by accumulating mutations in the antibody sequence. Mapping out the antibody-antigen affinity lands…
Blindfold learning of an accurate neural metric
Christophe Gardella, Olivier Marre, Thierry Mora
The brain has no direct access to physical stimuli, but only to the spiking activity evoked in sensory organs. It is unclear how the brain can structure its representation of the w…
Method for identification of condition-associated public antigen receptor sequences
Mikhail V. Pogorelyy, Anastasia A. Minervina, Dmitriy M. Chudakov +4
Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire…
Disorder and the neural representation of complex odors: smelling in the real world
Kamesh Krishnamurthy, Ann M Hermundstad, Thierry Mora +2
Animals smelling in the real world use a small number of receptors to sense a vast number of natural molecular mixtures, and proceed to learn arbitrary associations between odors a…
IGoR: a tool for high-throughput immune repertoire analysis
Quentin Marcou, Thierry Mora, Aleksandra M Walczak
High throughput immune repertoire sequencing is promising to lead to new statistical diagnostic tools for medicine and biology. Successful implementations of these methods require…
Transitions in optimal adaptive strategies for populations in fluctuating environments
Andreas Mayer, Thierry Mora, Olivier Rivoire +1
Biological populations are subject to fluctuating environmental conditions. Different adaptive strategies can allow them to cope with these fluctuations: specialization to one part…