811 citations · 7.3k across the 89 of their papers we have counts for
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Building general Langevin models from discrete data sets
Federica Ferretti, Victor Chardès, Thierry Mora +2
Many living and complex systems exhibit second order emergent dynamics. Limited experimental access to the configurational degrees of freedom results in data that appears to be gen…
Inferring the immune response from repertoire sequencing
Maximilian Puelma Touzel, Aleksandra M. Walczak, Thierry Mora
High-throughput sequencing of B- and T-cell receptors makes it possible to track immune repertoires across time, in different tissues, and in acute and chronic diseases or in healt…
On generative models of T-cell receptor sequences
Giulio Isacchini, Zachary Sethna, Yuval Elhanati +3
T-cell receptors (TCR) are key proteins of the adaptive immune system, generated randomly in each individual, whose diversity underlies our ability to recognize infections and mali…
Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones
Anastasia A. Minervina, Mikhail V. Pogorelyy, Ekaterina A. Komech +9
The diverse repertoire of T-cell receptors (TCR) plays a key role in the adaptive immune response to infections. Previous studies show that secondary responses to the yellow fever…
Physical limit to concentration sensing in a changing environment
Thierry Mora, Ilya Nemenman
Cells adapt to changing environments by sensing ligand concentrations using specific receptors. The accuracy of sensing is ultimately limited by the finite number of ligand molecul…
Quantitative Immunology for Physicists
Grégoire Altan-Bonnet, Thierry Mora, Aleksandra M. Walczak
The adaptive immune system is a dynamical, self-organized multiscale system that protects vertebrates from both pathogens and internal irregularities, such as tumours. For these re…