811 citations · 7.3k across the 89 of their papers we have counts for
7 papers · 1 filter
Diversity of immune strategies explained by adaptation to pathogen statistics
Andreas Mayer, Thierry Mora, Olivier Rivoire +1
Biological organisms have evolved a wide range of immune mechanisms to defend themselves against pathogens. Beyond molecular details, these mechanisms differ in how protection is a…
Local equilibrium in bird flocks
Thierry Mora, Aleksandra M. Walczak, Lorenzo Del Castello +6
The correlated motion of flocks is an instance of global order emerging from local interactions. An essential difference with analogous ferromagnetic systems is that flocks are act…
repgenHMM: a dynamic programming tool to infer the rules of immune receptor generation from sequence data
Yuval Elhanati, Quentin Marcou, Thierry Mora +1
The diversity of the immune repertoire is initially generated by random rearrangements of the receptor gene during early T and B cell development. Rearrangement scenarios are compo…
Habitat Fluctuations Drive Species Covariation in the Human Microbiota
Charles K. Fisher, Thierry Mora, Aleksandra M. Walczak
Two species with similar resource requirements respond in a characteristic way to variations in their habitat -- their abundances rise and fall in concert. We use this idea to lear…
Fluctuating fitness shapes the clone size distribution of immune repertoires
Jonathan Desponds, Thierry Mora, Aleksandra M. Walczak
The adaptive immune system relies on the diversity of receptors expressed on the surface of B and T-cells to protect the organism from a vast amount of pathogenic threats. The prol…
Physical limit to concentration sensing amid spurious ligands
Thierry Mora
To adapt their behaviour in changing environments, cells sense concentrations by binding external ligands to their receptors. However, incorrect ligands may bind nonspecifically to…