output
19982025
most citedSecond-generation PLINK: rising to the challenge of larger and richer datasets

14.3k citations

Showing 2017Show all

9 papers · 1 filter

cs.CV2017★ 870 cited

End-to-end Training for Whole Image Breast Cancer Diagnosis using An All Convolutional Design

Li Shen

We develop an end-to-end training algorithm for whole-image breast cancer diagnosis based on mammograms. It requires lesion annotations only at the first stage of training. After t…

q-bio.PE2017★ 25 cited

Combination interventions for Hepatitis C and Cirrhosis reduction among people who inject drugs: An agent-based, networked population simulation experiment

Bilal Khan, Ian Duncan, Mohamad Saad +7

Hepatitis C virus (HCV) infection is endemic in people who inject drugs (PWID), with prevalence estimates above 60 percent for PWID in the United States. Previous modeling studies…

cs.NE2017★ 141 cited

full-FORCE: A Target-Based Method for Training Recurrent Networks

Brian DePasquale, Christopher J. Cueva, Kanaka Rajan +2

Trained recurrent networks are powerful tools for modeling dynamic neural computations. We present a target-based method for modifying the full connectivity matrix of a recurrent n…

astro-ph.GA2017★ 8 cited

The Grism Lens-Amplified Survey from Space (GLASS). XII. Spatially Resolved Galaxy Star Formation Histories and True Evolutionary Paths at z > 1

L. E. Abramson, A. B. Newman, T. Treu +12

Modern data empower observers to describe galaxies as the spatially and biographically complex objects they are. We illustrate this through case studies of four, systems…

q-bio.QM2017★ 92 cited

Emerging whole-cell modeling principles and methods

Arthur P. Goldberg, Balázs Szigeti, Yin Hoon Chew +3

Whole-cell computational models aim to predict cellular phenotypes from genotype by representing the entire genome, the structure and concentration of each molecular species, each…

cs.CV2017★ 6 cited

Improving Dermoscopic Image Segmentation with Enhanced Convolutional-Deconvolutional Networks

Yading Yuan, Yeh-Chi Lo

Automatic skin lesion segmentation on dermoscopic images is an essential step in computer-aided diagnosis of melanoma. However, this task is challenging due to significant variatio…

cs.CV2017★ 870 cited

Deep Learning to Improve Breast Cancer Early Detection on Screening Mammography

Li Shen, Laurie R. Margolies, Joseph H. Rothstein +3

The rapid development of deep learning, a family of machine learning techniques, has spurred much interest in its application to medical imaging problems. Here, we develop a deep l…

cs.DL2017★ 128 cited

Sustainable computational science: the ReScience initiative

Nicolas P. Rougier, Konrad Hinsen, Frédéric Alexandre +42

Computer science offers a large set of tools for prototyping, writing, running, testing, validating, sharing and reproducing results, however computational science lags behind. In…

cs.CV2017★ 195 cited

Automatic skin lesion segmentation with fully convolutional-deconvolutional networks

Yading Yuan

This paper summarizes our method and validation results for the ISBI Challenge 2017 - Skin Lesion Analysis Towards Melanoma Detection - Part I: Lesion Segmentation