activity
20192022
most citedEstimating heterogeneous survival treatment effect in observational data using machine learning

78 citations · 92 across the 15 of their papers we have counts for

collaborators

15 papers

stat.ME2022★ 1 cited

Doubly robust estimation and sensitivity analysis for marginal structural quantile models

Chao Cheng, Liangyuan Hu, Fan Li

The marginal structure quantile model (MSQM) provides a unique lens to understand the causal effect of a time-varying treatment on the full distribution of potential outcomes. Unde…

stat.ME2022

A new method for clustered survival data]{A new method for clustered survival data: Estimation of treatment effect heterogeneity and variable selection

Liangyuan Hu

We recently developed a new method riAFT-BART to draw causal inferences about population treatment effect on patient survival from clustered and censored survival data while accoun…

stat.ME2022

A flexible approach for causal inference with multiple treatments and clustered survival outcomes

Liangyuan Hu, Jiayi Ji, Ronald D. Ennis +1

When drawing causal inferences about the effects of multiple treatments on clustered survival outcomes using observational data, we need to address implications of the multilevel d…

stat.ME2021

CIMTx: An R package for causal inference with multiple treatments using observational data

Liangyuan Hu, Jiayi Ji

CIMTx provides efficient and unified functions to implement modern methods for causal inferences with multiple treatments using observational data with a focus on binary outcomes.…

stat.ME2021★ 1 cited

Estimating the causal effects of multiple intermittent treatments with application to COVID-19

Liangyuan Hu, Jiayi Ji, Himanshu Joshi +2

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a…

stat.ME2021

A flexible approach for variable selection in large-scale healthcare database studies with missing covariate and outcome data

Jung-Yi Joyce Lin, Liangyuan Hu, Chuyue Huang +2

Prior work has shown that combining bootstrap imputation with tree-based machine learning variable selection methods can provide good performances achievable on fully observed data…

stat.ME2021★ 3 cited

Variable selection with missing data in both covariates and outcomes: Imputation and machine learning

Liangyuan Hu, Jung-Yi Joyce Lin, Jiayi Ji

The missing data issue is ubiquitous in health studies. Variable selection in the presence of both missing covariates and outcomes is an important statistical research topic but ha…

stat.ME2021★ 1 cited

Propensity Score Weighting Analysis of Survival Outcomes Using Pseudo-observations

Shuxi Zeng, Fan Li, Liangyuan Hu

Survival outcomes are common in comparative effectiveness studies and require unique handling because they are usually incompletely observed due to right-censoring. A ``once for al…

stat.ME2020

A flexible sensitivity analysis approach for unmeasured confounding with multiple treatments and a binary outcome with application to SEER-Medicare lung cancer data

Liangyuan Hu, Jungang Zou, Chenyang Gu +3

In the absence of a randomized experiment, a key assumption for drawing causal inference about treatment effects is the ignorable treatment assignment. Violations of the ignorabili…

stat.ME2020★ 1 cited

Estimation of causal effects of multiple treatments in healthcare database studies with rare outcomes

Liangyuan Hu, Chenyang Gu

The preponderance of large-scale healthcare databases provide abundant opportunities for comparative effectiveness research. Evidence necessary to making informed treatment decisio…

stat.AP2020★ 78 cited

Estimating heterogeneous survival treatment effect in observational data using machine learning

Liangyuan Hu, Jiayi Ji, Fan Li

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with surviva…

stat.ME2020★ 4 cited

Estimation of Causal Effects of Multiple Treatments in Observational Studies with a Binary Outcome

Liangyuan Hu, Chenyang Gu, Michael Lopez +2

There is a dearth of robust methods to estimate the causal effects of multiple treatments when the outcome is binary. This paper uses two unique sets of simulations to propose and…

stat.AP2019

Modeling the Causal Effect of Treatment Initiation Time on Survival: Application to HIV/TB Co-infection

Liangyuan Hu, Joseph W. Hogan, Ann W. Mwangi +1

The timing of antiretroviral therapy (ART) initiation for HIV and tuberculosis (TB) co-infected patients needs to be considered carefully. CD4 cell count can be used to guide decis…

stat.AP2019★ 3 cited

Causal comparative effectiveness analysis of dynamic continuous-time treatment initiation rules with sparsely measured outcomes and death

Liangyuan Hu, Joseph W. Hogan

Evidence supporting the current World Health Organization recommendations of early antiretroviral therapy (ART) initiation for adolescents is inconclusive. We leverage a large obse…

stat.ME2019

The Estimation of Causal Effects of Multiple Treatments in Observational Studies Using Bayesian Additive Regression Trees

Chenyang Gu, Michael J. Lopez, Liangyuan Hu

There is currently a dearth of appropriate methods to estimate the causal effects of multiple treatments when the outcome is binary. For such settings, we propose the use of nonpar…