output
19982025
most citedSecond-generation PLINK: rising to the challenge of larger and richer datasets

14.3k citations

Showing 2013Show all

6 papers · 1 filter

q-bio.SC2013★ 7 cited

Self-regulating genes. Exact steady state solution by using Poisson Representation

Istvan P. Sugar, Istvan Simon

Systems biology studies the structure and behavior of complex gene regulatory networks. One of its aims is to develop a quantitative understanding of the modular components that co…

stat.ML2013★ 3 cited

Multiscale Dictionary Learning for Estimating Conditional Distributions

Francesca Petralia, Joshua Vogelstein, David B. Dunson

Nonparametric estimation of the conditional distribution of a response given high-dimensional features is a challenging problem. It is important to allow not only the mean but also…

q-bio.MN2013★ 85 cited

Dynamic Modeling of the Interaction Between Autophagy and Apoptosis in Mammalian Cells

I. Tavassoly, J. Parmar, A. N. Shajahan-Haq +3

Autophagy is a conserved biological stress response in mammalian cells that is responsible for clearing damaged proteins and organelles from the cytoplasm and recycling their conte…

stat.ME2013

Functional and Parametric Estimation in a Semi- and Nonparametric Model with Application to Mass-Spectrometry Data

Weiping Ma, Yang Feng, Kani Chen +1

Motivated by modeling and analysis of mass-spectrometry data, a semi- and nonparametric model is proposed that consists of a linear parametric component for individual location and…

q-bio.GN2013★ 4.8k cited

Bayesian Test for Colocalisation Between Pairs of Genetic Association Studies Using Summary Statistics

Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt +4

Genetic association studies, in particular the genome-wide association study design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases a…

cs.AI2013★ 1 cited

Imprecise Meanings as a Cause of Uncertainty in Medical Knowledge-Based Systems

Steven J. Henkind

There has been a considerable amount of work on uncertainty in knowledge-based systems. This work has generally been concerned with uncertainty arising from the strength of inferen…