output
19982025
most citedSecond-generation PLINK: rising to the challenge of larger and richer datasets

14.3k citations

Showing 2007Show all

5 papers · 1 filter

q-bio.MN2007★ 42 cited

Functions of Bifans in Context of Multiple Regulatory Motifs in Signaling Networks

Azi Lipshtat, Sudarshan P. Purushothaman, Ravi Iyengar +1

Representation of intracellular signaling networks as directed graphs allows for the identification of regulatory motifs. Regulatory motifs are groups of nodes with the same connec…

q-bio.QM2007★ 32 cited

Time and length scales of autocrine signals in three dimensions

Mathieu Coppey, Alexander M. Berezhkovskii, Stuart C. Sealfon +1

A model of autocrine signaling in cultures of suspended cells is developed on the basis of the effective medium approximation. The fraction of autocrine ligands, the mean and distr…

q-bio.QM2007★ 10 cited

An "All Possible Steps" Approach to the Accelerated Use of Gillespie's Algorithm

Azi Lipshtat

Many physical and biological processes are stochastic in nature. Computational models and simulations of such processes are a mathematical and computational challenge. The basic st…

q-bio.MN2007

Deterministic and Stochastic Simulations of Simple Genetic Circuits

Ofer Biham, Nathalie Q. Balaban, Adiel Loinger +2

We analyze three simple genetic circuits which involve transcriptional regulation and feedback: the autorepressor, the switch and the repressilator, that consist of one, two and th…

q-bio.MN2007

Stochastic Simulations of Genetic Switch Systems

Adiel Loinger, Azi Lipshtat, Nathalie Q. Balaban +1

Genetic switch systems with mutual repression of two transcription factors are studied using deterministic methods (rate equations) and stochastic methods (the master equation and…