83 citations · 172 across the 8 of their papers we have counts for
21 papers
DNA topology dictates strength and flocculation in DNA-microtubule composites
Karthik R. Peddireddy, Davide Michieletto, Gina Aguirre +3
Polymer composites are ubiquitous in biology and industry alike, owing to their emergent desirable mechanical properties not attainable in single-species systems. At the same time,…
Dynamical Entanglement and Cooperative Dynamics in Entangled Solutions of Ring and Linear Polymers
Davide Michieletto, Takahiro Sakaue
Understanding how entanglements affect the behaviour of polymeric complex fluids is an open challenge in many fields. To elucidate the nature and consequence of entanglements in de…
Simplifying Topological Entanglements by Entropic Competition of Slip-Links
Andrea Bonato, Davide Marenduzzo, Davide Michieletto
Topological entanglements are abundant, and often detrimental, in polymeric systems in biology and materials science. Here we theoretically investigate the topological simplificati…
Polymer Modelling Predicts Chromosome Reorganisation in Senescence
Michael Chiang, Davide Michieletto, Chris A. Brackley +4
Lamina-associated domains (LADs) cover a large part of the human genome and are thought to play a major role in shaping the nuclear architectural landscape. Here, we perform polyme…
Simulating topological domains in human chromosomes with a fitting-free model
C. A. Brackley, D. Michieletto, F. Mouvet +4
We discuss a polymer model for the 3D organization of human chromosomes. A chromosome is represented by a string of beads, with each bead being "colored" according to 1D bioinforma…
Non-Equilibrium Effects of Molecular Motors on Polymers
M. Foglino, E. Locatelli, C. A. Brackley +3
We present a generic coarse-grained model to describe molecular motors acting on polymer substrates, mimicking, for example, RNA polymerase on DNA or kinesin on microtubules. The p…