148 citations · 1k across the 43 of their papers we have counts for
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Synergy of Topoisomerase and Structural-Maintenance-of-Chromosomes Proteins Creates a Universal Pathway to Simplify Genome Topology
Enzo Orlandini, Davide Marenduzzo, Davide Michieletto
Topological entanglements severely interfere with important biological processes. For this reason, genomes must be kept unknotted and unlinked during most of a cell cycle. Type II…
Magnetic Polymer Models for Epigenomic Organisation and Phase Separation
Davide Coli, Davide Michieletto, Davide Marenduzzo +1
The genetic instructions stored in the genome require an additional layer of information to robustly determine cell fate. This additional regulation is provided by the interplay be…
Physical Principles of Retroviral Integration in the Human Genome
Davide Michieletto, Marina Lusic, Davide Marenduzzo +1
Certain retroviruses, including HIV, insert their DNA in a non-random fraction of the host genome via poorly understood selection mechanisms. Here, we develop a biophysical model f…