148 citations · 1k across the 43 of their papers we have counts for
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Rings in Random Environments: Sensing Disorder Through Topology
Davide Michieletto, Marco Baiesi, Enzo Orlandini +1
In this paper we study the role of topology in DNA gel electrophoresis experiments via molecular dynamics simulations. The gel is modelled as a 3D array of obstacles from which hal…
Topology Regulation during Replication of the Kinetoplast DNA
Davide Michieletto, Davide Marenduzzo, Matthew S. Turner
We study theoretically the replication of Kinetoplast DNA consisting of several thousands separate mini-circles found in organisms of the class Kinetoplastida. When the cell is not…
Is the Kinetoplast DNA a Percolating Network of Linked Rings at its Critical Point?
Davide Michieletto, Davide Marenduzzo, Enzo Orlandini
In this work we present a computational study of the Kinetoplast genome, modelled as a large number of semiflexible unknotted loops, which are allowed to link with each other. As t…
Dynamics of Self-Threading Ring Polymers in a Gel
Davide Michieletto, Davide Marenduzzo, Enzo Orlandini +2
We study of the dynamics of ring polymers confined to diffuse in a background gel at low concentrations. We do this in order to probe the inter-play between topology and dynamics i…