148 citations · 1k across the 43 of their papers we have counts for
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Single-Molecule Morphology of Topologically Digested Olympic Networks
Saminathan Ramakrishnan, Zihao Chen, Yair Augusto Gutierrez Fosado +5
The kinetoplast DNA (kDNA) is the archetype of a two-dimensional Olympic network, composed of thousands of DNA minicircles and found in the mitochondrion of certain parasites. The…
Spontaneous Unidirectional Loop Extrusion Emerges from Symmetry Breaking of SMC Extension
Andrea Bonato, Jae-Won Jang, Kyoung-Wook Moon +2
DNA loop extrusion is arguably one of the most important players in genome organization. The precise mechanism by which loop extruding factors (LEFs) work is still unresolved and m…
Loops are Geometric Catalysts for DNA Integration
Cleis Battaglia, Davide Michieletto
The insertion of HIV and other DNA elements within genomes underpins both genetic diversity and disease when unregulated. Most of these insertions are not random and occupy specifi…
Geometric Learning of Knot Topology
Joseph Lahoud Sleiman, Filippo Conforto, Yair Augusto Gutierrez Fosado +1
Knots are deeply entangled with every branch of science. One of the biggest open challenges in knot theory is to formalise a knot invariant that can unambiguously and efficiently d…