148 citations · 1k across the 43 of their papers we have counts for
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Physical Principles of Retroviral Integration in the Human Genome
Davide Michieletto, Marina Lusic, Davide Marenduzzo +1
Certain retroviruses, including HIV, insert their DNA in a non-random fraction of the host genome via poorly understood selection mechanisms. Here, we develop a biophysical model f…
Shaping Epigenetic Memory via Genomic Bookmarking
Davide Michieletto, Michael Chiang, Davide Coli +4
Reconciling the stability of epigenetic patterns with the rapid turnover of histone modifications and their adaptability to external stimuli is an outstanding challenge. Here, we p…
Chromosome-wide simulations uncover folding pathway and 3D organization of interphase chromosomes
Davide Michieletto, Davide Marenduzzo, Ajazul H. Wani
Three-dimensional interphase organization of metazoan genomes has been linked to cellular identity. However, the principles governing 3D interphase genome architecture and its fait…