1.3k citations · 3.4k across the 81 of their papers we have counts for
81 papers
Predicting influenza H3N2 vaccine efficacy from evolution of the dominant epitope
Melia E. Bonomo, Michael W. Deem
We predict vaccine efficacy with a measure of antigenic distance between influenza A(H3N2) and candidate vaccine viruses based on amino acid substitutions in the dominant epitopes.…
The physicist's guide to one of biotechnology's hottest new topics: CRISPR-Cas
Melia E. Bonomo, Michael W. Deem
Clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated proteins (Cas) constitute a multi-functional, constantly evolving immune system in bacteria…
Static and dynamic measures of human brain connectivity predict complementary aspects of human cognitive performance
Aurora I. Ramos-Nuñez, Simon Fischer-Baum, Randi Martin +3
In cognitive network neuroscience, the connectivity and community structure of the brain network is related to cognition. Much of this research has focused on two measures of conne…
Brain Modularity Mediates the Relation between Task Complexity and Performance
Qiuhai Yue, Randi Martin, Simon Fischer-Baum +3
Recent work in cognitive neuroscience has focused on analyzing the brain as a network, rather than as a collection of independent regions. Prior studies taking this approach have f…
Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma
Fengdan Ye, Dongya Jia, Mingyang Lu +2
Abnormal metabolism is an emerging hallmark of cancer. Cancer cells utilize both aerobic glycolysis and oxidative phosphorylation (OXPHOS) for energy production and biomass synthes…
The standard genetic code facilitates exploration of the space of functional nucleotide sequences
Shubham Tripathi, Michael W. Deem
The standard genetic code is well known to be optimized for minimizing the phenotypic effects of single nucleotide substitutions, a property that was likely selected for during the…