1.3k citations · 3.4k across the 81 of their papers we have counts for
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Evolution: Life has Evolved to Evolve
Michael W. Deem
Jim Shapiro synthesizes a great many observations about the mechanisms of evolution to reach the remarkable conclusion that large-scale modification, exchange, and rearrangement of…
Prediction of heart rate response to conclusion of spontaneous breathing trial by fluctuation dissipation theory
Man Chen, Liang Ren Niestemski, Robert Prevost +5
The non-equilibrium fluctuation dissipation theorem is applied to predict how critically ill patients respond to treatment, based upon data currently collected by standard hospital…
Physical Model of the Immune Response of Bacteria Against Bacteriophage Through the Adaptive CRISPR-Cas Immune System
Pu Han, Liang Ren Niestemski, Jeffrey E. Barrick +1
Bacteria and archaea have evolved an adaptive, heritable immune system that recognizes and protects against viruses or plasmids. This system, known as the CRISPR-Cas system, allows…
Hierarchy of Gene Expression Data is Predictive of Future Breast Cancer Outcome
Man Chen, Michael W. Deem
We calculate measures of hierarchy in gene and tissue networks of breast cancer patients. We find that the likelihood of metastasis in the future is correlated with increased value…