83 citations · 91 across the 8 of their papers we have counts for
4 papers · 1 filter
Markov Chains of Infinite Order and Asymptotic Satisfaction of Balance: Application to the Adaptive Integration Method
David J. Earl, Michael W. Deem
Adaptive Monte Carlo methods can be viewed as implementations of Markov chains with infinite memory. We derive a general condition for the convergence of a Monte Carlo method whose…
Epitope analysis for influenza vaccine design
Enrique T. Munoz, Michael W. Deem
Until now, design of the annual influenza vaccine has relied on phylogenetic or whole-sequence comparisons of the viral coat proteins hemagglutinin and neuraminidase, with vaccine…
Modulation of Base Specific Mutation and Recombination Rates Enables Functional Adaptation within the Context of the Genetic Code
Taison Tan, Leonard D. Bogarad, Michael W. Deem
The persistence of life requires populations to adapt at a rate commensurate with the dynamics of their environment. Successful populations that inhabit highly variable environment…
Optimal Allocation of Replicas to Processors in Parallel Tempering Simulations
David J. Earl, Michael W. Deem
The optimal allocation of replicas to a homogeneous or heterogenous set of processors is derived for parallel tempering simulations on multi-processor machines. In the general case…