Formation of polyhedral vesicles and polygonal membrane tubes induced by banana-shaped proteins

Abstract

The shape transformations of fluid membranes induced by curved protein rods are studied using meshless membrane simulations. The rod assembly at low rod density induces a flat membrane tube and oblate vesicle. It is found that the polyhedral shapes are stabilized at high rod densities. The discrete shape transition between triangular and buckled discoidal tubes is obtained and their curvature energies are analyzed by a simple geometric model. For vesicles, triangular hosohedron and elliptic-disk shapes are formed in equilibrium, whereas tetrahedral and triangular prism shapes are obtained as metastable states.

9 pages, 9 figures, J. Chem. Phys. in press

References in corpus (10)

• Virus shapes and buckling transitions in spherical shells
• Fluid membranes can drive linear aggregation of adsorbed spherical nanoparticles
• Membrane mediated aggregation of curvature inducing nematogens and membrane tubulation
• Budding and vesiculation induced by conical membrane inclusions
• Anisotropic surface tension of buckled fluid membrane
• Two- or three-step assembly of banana-shaped proteins coupled with shape transformation of lipid membranes
• Role of disclinations in determining the morphology of deformable fluid interfaces
• Structure formation in binary mixtures of surfactants: vesicle opening-up to bicelles and octopus-like micelles
• Shape transformations of toroidal vesicles
• Minimal Bending Energies of Bilayer Polyhedra

Cited by in corpus (15)

• Membrane tubule formation by banana-shaped proteins with or without transient network structure
• Membrane morphologies induced by arc-shaped scaffolds are determined by arc angle and coverage
• Acceleration and suppression of banana-shaped-protein-induced tubulation by addition of small membrane inclusions of isotropic spontaneous curvatures
• Shape transition from elliptical to cylindrical membrane tubes induced by chiral crescent-shaped protein rods
• Vesicle budding induced by binding of curvature-inducing proteins
• Shape deformation of lipid membranes by banana-shaped protein rods: Comparison with isotropic inclusions and membrane rupture
• Membrane shape deformation induced by curvature-inducing proteins consisting of chiral crescent binding and intrinsically disordered domains
• Binding of anisotropic curvature-inducing proteins onto membrane tubes
• Cup-to-vesicle transition of a fluid membrane with spontaneous curvature
• Binding of Curvature-Inducing Proteins onto Biomembranes
• Shape transitions of high-genus fluid vesicles
• Binding of curvature-inducing proteins onto tethered vesicles
• Membrane domain formation induced by binding/unbinding of curvature-inducing molecules onto both membrane surfaces
• Curvature-sensing and generation by membrane proteins: a review
• Estimation of anisotropic bending rigidities and spontaneous curvatures of crescent curvature-inducing proteins from tethered-vesicle experimental data