Budding and vesiculation induced by conical membrane inclusions
arXiv:0910.3067 · doi:10.1103/PhysRevE.80.031901
Abstract
Conical inclusions in a lipid bilayer generate an overall spontaneous curvature of the membrane that depends on concentration and geometry of the inclusions. Examples are integral and attached membrane proteins, viruses, and lipid domains. We propose an analytical model to study budding and vesiculation of the lipid bilayer membrane, which is based on the membrane bending energy and the translational entropy of the inclusions. If the inclusions are placed on a membrane with similar curvature radius, their repulsive membrane-mediated interaction is screened. Therefore, for high inclusion density the inclusions aggregate, induce bud formation, and finally vesiculation. Already with the bending energy alone our model allows the prediction of bud radii. However, in case the inclusions induce a single large vesicle to split into two smaller vesicles, bending energy alone predicts that the smaller vesicles have different sizes whereas the translational entropy favors the formation of equal-sized vesicles. Our results agree well with those of recent computer simulations.
11 pages, 12 figures
References in corpus (7)
- Interaction of Conical Membrane Inclusions: Effect of Lateral Tension
- A simple patchy colloid model for the phase behavior of lysozyme dispersions
- Fluctuation-Induced Interactions between Rods on a Membrane
- Fluctuation-Induced Interactions between Rods on Membranes and Interfaces
- Effective adhesion strength of specifically bound vesicles
- Dynamic phase separation of fluid membranes with rigid inclusions
- Scale-dependent rigidity of polymer-ornamented membranes
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