output
20062025
most citedEnhancing Clinical Concept Extraction with Contextual Embeddings

338 citations

135 papers

cs.CL2025

Clinical Document Metadata Extraction: A Scoping Review

Kurt Miller, Qiuhao Lu, William Hersh +4

Clinical document metadata, such as document type, structure, author role, medical specialty, and encounter setting, is essential for accurate interpretation of information capture…

stat.ME2025

Bayesian Geostatistical Modeling for Cluster Randomized Trials

Jooyeon Lee, M. S., Evan Kwiatkowski +1

Cluster randomized trials (CRTs) offer a practical alternative for addressing logistical challenges and ensuring feasibility in community health, education, and prevention studies,…

cs.CL2025★ 1 cited

Memorization in Large Language Models in Medicine: Prevalence, Characteristics, and Implications

Anran Li, Lingfei Qian, Mengmeng Du +18

Large Language Models (LLMs) have demonstrated significant potential in medicine, with many studies adapting them through continued pre-training or fine-tuning on medical data to e…

cs.CL2025

Synthesized Annotation Guidelines are Knowledge-Lite Boosters for Clinical Information Extraction

Enshuo Hsu, Martin Ugbala, Krishna Kumar Kookal +4

Generative information extraction using large language models, particularly through few-shot learning, has become a popular method. Recent studies indicate that providing a detaile…

q-bio.NC2025★ 119 cited

KMT2B-related disorders: expansion of the phenotypic spectrum and long-term efficacy of deep brain stimulation

L Cif, D Demailly, JP Lin +112

Heterozygous mutations in KMT2B are associated with an early-onset, progressive, and often complex dystonia (DYT28). Key characteristics of typical disease include focal motor feat…

cs.LG2024★ 14 cited

LLM-IE: A Python Package for Generative Information Extraction with Large Language Models

Enshuo Hsu, Kirk Roberts

Objectives: Despite the recent adoption of large language models (LLMs) for biomedical information extraction, challenges in prompt engineering and algorithms persist, with no dedi…

cs.CL2024★ 30 cited

A Comparative Study of Recent Large Language Models on Generating Hospital Discharge Summaries for Lung Cancer Patients

Yiming Li, Fang Li, Kirk Roberts +3

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care.…

physics.med-ph2024★ 2 cited

OAR-Weighted Dice Score: A spatially aware, radiosensitivity aware metric for target structure contour quality assessment

Lucas McCullum, Kareem A. Wahid, Barbara Marquez +1

The Dice Similarity Coefficient (DSC) is the current de facto standard to determine agreement between a reference segmentation and one generated by manual / auto-contouring approac…

cs.CL2024★ 3 cited

Suicide Phenotyping from Clinical Notes in Safety-Net Psychiatric Hospital Using Multi-Label Classification with Pre-Trained Language Models

Zehan Li, Yan Hu, Scott Lane +7

Accurate identification and categorization of suicidal events can yield better suicide precautions, reducing operational burden, and improving care quality in high-acuity psychiatr…

cs.LG2024★ 6 cited

Explainable Diagnosis Prediction through Neuro-Symbolic Integration

Qiuhao Lu, Rui Li, Elham Sagheb +5

Diagnosis prediction is a critical task in healthcare, where timely and accurate identification of medical conditions can significantly impact patient outcomes. Traditional machine…

cs.LG2024★ 1 cited

A Generative Framework for Predictive Modeling of Multiple Chronic Conditions Using Graph Variational Autoencoder and Bandit-Optimized Graph Neural Network

Julian Carvajal Rico, Adel Alaeddini, Syed Hasib Akhter Faruqui +2

Predicting the emergence of multiple chronic conditions (MCC) is crucial for early intervention and personalized healthcare, as MCC significantly impacts patient outcomes and healt…

cs.CL2024★ 7 cited

Robust Privacy Amidst Innovation with Large Language Models Through a Critical Assessment of the Risks

Yao-Shun Chuang, Atiquer Rahman Sarkar, Yu-Chun Hsu +2

This study examines integrating EHRs and NLP with large language models (LLMs) to improve healthcare data management and patient care. It focuses on using advanced models to create…

eess.IV2024★ 14 cited

BraTS-PEDs: Results of the Multi-Consortium International Pediatric Brain Tumor Segmentation Challenge 2023

Anahita Fathi Kazerooni, Nastaran Khalili, Xinyang Liu +77

Pediatric central nervous system tumors are the leading cause of cancer-related deaths in children. The five-year survival rate for high-grade glioma in children is less than 20%.…

cs.CL2024★ 11 cited

Leveraging Large Language Models for Knowledge-free Weak Supervision in Clinical Natural Language Processing

Enshuo Hsu, Kirk Roberts

The performance of deep learning-based natural language processing systems is based on large amounts of labeled training data which, in the clinical domain, are not easily availabl…

cs.CL2024★ 40 cited

Relation Extraction Using Large Language Models: A Case Study on Acupuncture Point Locations

Yiming Li, Xueqing Peng, Jianfu Li +6

In acupuncture therapy, the accurate location of acupoints is essential for its effectiveness. The advanced language understanding capabilities of large language models (LLMs) like…

stat.AP2024★ 2 cited

Are Made and Missed Different? An analysis of Field Goal Attempts of Professional Basketball Players via Depth Based Testing Procedure

Kai Qi, Guanyu Hu, Wei Wu

In this paper, we develop a novel depth-based testing procedure on spatial point processes to examine the difference in made and missed field goal attempts for NBA players. Specifi…

physics.med-ph2024★ 18 cited

Development of novel ionization chambers for reference dosimetry in electron FLASH radiotherapy

Kevin Liu, Shannon Holmes, Ahtesham Ullah Khan +4

The aim of this study was to optimize the design and performance of parallel plate ion chambers for use in ultra-high dose rate (UHDR) dosimetry applications, and evaluate their po…

physics.med-ph2024★ 3 cited

Characterization of a novel time-resolved, real-time scintillation dosimetry system for ultra-high dose rate radiation therapy applications

Alexander Baikalov, Daline Tho, Kevin Liu +3

Background: Scintillation dosimetry has promising qualities for ultra-high dose rate (UHDR) radiotherapy (RT), but no system has shown compatibility with mean dose rates ($\bar{DR}…

cs.CL2024★ 35 cited

De-identification is not enough: a comparison between de-identified and synthetic clinical notes

Atiquer Rahman Sarkar, Yao-Shun Chuang, Noman Mohammed +1

For sharing privacy-sensitive data, de-identification is commonly regarded as adequate for safeguarding privacy. Synthetic data is also being considered as a privacy-preserving alt…

q-bio.QM2024★ 28 cited

Advancing bioinformatics with large language models: components, applications and perspectives

Jiajia Liu, Mengyuan Yang, Yankai Yu +4

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language pro…

stat.AP2023★ 1 cited

Bayesian Nonparametric Clustering with Feature Selection for Spatially Resolved Transcriptomics Data

Bencong Zhu, Guanyu Hu, Yang Xie +3

The advent of next-generation sequencing-based spatially resolved transcriptomics (SRT) techniques has reshaped genomic studies by enabling high-throughput gene expression profilin…

cs.CV2023★ 14 cited

The TopCoW Challenge -- Topology-Aware Circle of Willis Segmentation for CT and MR Angiography

Kaiyuan Yang, Fabio Musio, Yihui Ma +112

The Circle of Willis (CoW) is an important network of arteries connecting major circulations of the brain. Its vascular architecture is believed to influence the risk, severity, an…

cs.CL2023★ 2 cited

Use GPT-J Prompt Generation with RoBERTa for NER Models on Diagnosis Extraction of Periodontal Diagnosis from Electronic Dental Records

Yao-Shun Chuang, Xiaoqian Jiang, Chun-Teh Lee +4

This study explored the usability of prompt generation on named entity recognition (NER) tasks and the performance in different settings of the prompt. The prompt generation by GPT…

stat.ME2023

Evaluating the effects of high-throughput structural neuroimaging predictors on whole-brain functional connectome outcomes via network-based vector-on-matrix regression

Tong Lu, Yuan Zhang, Vince Lyzinski +4

The joint analysis of multimodal neuroimaging data is critical in the field of brain research because it reveals complex interactive relationships between neurobiological structure…