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- European Bioinformatics InstituteGB18 papers
- University of CambridgeGB14 papers
- The Gurdon InstituteGB10 papers
- University College LondonGB9 papers
- Centre National de la Recherche ScientifiqueFR6 papers
- Wellcome / EPSRC Centre for Interventional and Surgical SciencesGB6 papers
- InsermFR3 papers
- Institute of Science and Technology AustriaAT3 papers
- Institut national de recherche en sciences et technologies du numériqueFR3 papers
- National Center for Tumor DiseasesDE3 papers
- SIB Swiss Institute of BioinformaticsCH3 papers
- Wellcome/MRC Cambridge Stem Cell InstituteGB3 papers
4 papers · 1 filter
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
Michael P. Menden, Francesco Iorio, Mathew Garnett +4
Predicting the response of a specific cancer to a therapy is a major goal in modern oncology that should ultimately lead to a personalised treatment. High-throughput screenings of…
Revisiting the Training of Logic Models of Protein Signaling Networks with a Formal Approach based on Answer Set Programming
Santiago Videla, Carito Guziolowski, Federica Eduati +4
A fundamental question in systems biology is the construction and training to data of mathematical models. Logic formalisms have become very popular to model signaling networks bec…
Change-Point Detection in Time-Series Data by Relative Density-Ratio Estimation
Song Liu, Makoto Yamada, Nigel Collier +1
The objective of change-point detection is to discover abrupt property changes lying behind time-series data. In this paper, we present a novel statistical change-point detection a…
Optimal Placement of Origins for DNA Replication
Jens Karschau, J. Julian Blow, Alessandro P. S. de Moura
DNA replication is an essential process in biology and its timing must be robust so that cells can divide properly. Random fluctuations in the formation of replication starting poi…