83 citations · 230 across the 6 of their papers we have counts for
6 papers
Stem cell lineage survival as a noisy competition for niche access
Bernat Corominas-Murtra, Colinda L. G. J. Scheele, Kasumi Kishi +4
Understanding to what extent stem cell potential is a cell-intrinsic property, or an emergent behavior coming from global tissue dynamics and geometry, is a key outstanding questio…
Universality of clone dynamics during tissue development
Steffen Rulands, Fabienne Lescroart, Samira Chabab +7
The emergence of complex organs is driven by the coordinated proliferation, migration and differentiation of precursor cells. The fate behaviour of these cells is reflected in the…
Competition for Stem Cell Fate Determinants as a Mechanism for Tissue Homeostasis
David J Jörg, Yu Kitadate, Shosei Yoshida +1
Stem cells maintain tissues by generating differentiated cell types while simultaneously self-renewing their own population. The mechanisms that allow stem cell populations to func…
Extreme value statistics of mutation accumulation in renewing cell populations
Philip Greulich, Benjamin D. Simons
The emergence of a predominant phenotype within a cell population is often triggered by a rare accumulation of DNA mutations in a single cell. For example, tumors may be initiated…
Mechanism of murine epidermal maintenance: Cell division and the Voter Model
Allon M. Klein, David P. Doupe, Philip H. Jones +1
This paper presents an interesting experimental example of voter-model statistics in biology. In recent work on mouse tail-skin, where proliferating cells are confined to a two-dim…
Kinetics of cell division in epidermal maintenance
Allon M. Klein, David P. Doupe, Philip H. Jones +1
The rules governing cell division and differentiation are central to understanding the mechanisms of development, aging and cancer. By utilising inducible genetic labelling, recent…