output
20142024
most citedSARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways

2.7k citations

13 papers

q-bio.TO2024

The IBEX Imaging Knowledge-Base: A Community Resource Enabling Adoption and Development of Immunofluoresence Imaging Methods

Ziv Yaniv, Ifeanyichukwu U. Anidi, Leanne Arakkal +59

The iterative bleaching extends multiplexity (IBEX) Knowledge-Base is a central portal for researchers adopting IBEX and related 2D and 3D immunofluorescence imaging methods. The d…

q-bio.TO2024★ 1 cited

The IBEX Knowledge-Base: Achieving more together with open science

Andrea J. Radtke, Ifeanyichukwu Anidi, Leanne Arakkal +55

Iterative Bleaching Extends multipleXity (IBEX) is a versatile method for highly multiplexed imaging of diverse tissues. Based on open science principles, we created the IBEX Knowl…

physics.bio-ph2022★ 11 cited

Review: How dynamic prestress governs the shape of living systems, from the subcellular to tissue scale

Alexander Erlich, Jocelyn Étienne, Jonathan Fouchard +1

Cells and tissues change shape both to carry out their function and during pathology. In most cases, these deformations are driven from within the systems themselves. This is permi…

physics.optics2021★ 34 cited

Super-resolution structured illumination microscopy: past, present and future

Kirti Prakash, Benedict Diederich, Stefanie Reichelt +2

Structured illumination microscopy (SIM) has emerged as an essential technique for 3D and live-cell super-resolution imaging. However, to date, there has not been a dedicated works…

q-bio.CB2020★ 2.7k cited

SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways

Waradon Sungnak, Ni Huang, Christophe Bécavin +2

The SARS-CoV-2 coronavirus, the etiologic agent responsible for COVID-19 coronavirus disease, is a global threat. To better understand viral tropism, we assessed the RNA expression…

cond-mat.dis-nn2020★ 40 cited

Stem cell lineage survival as a noisy competition for niche access

Bernat Corominas-Murtra, Colinda L. G. J. Scheele, Kasumi Kishi +4

Understanding to what extent stem cell potential is a cell-intrinsic property, or an emergent behavior coming from global tissue dynamics and geometry, is a key outstanding questio…

q-bio.TO2019★ 54 cited

Universality of clone dynamics during tissue development

Steffen Rulands, Fabienne Lescroart, Samira Chabab +7

The emergence of complex organs is driven by the coordinated proliferation, migration and differentiation of precursor cells. The fate behaviour of these cells is reflected in the…

physics.med-ph2018★ 40 cited

Quantitative phase and polarisation endoscopy applied to detection of early oesophageal tumourigenesis

George S. D. Gordon, James Joseph, Maria P. Alcolea +9

Phase and polarisation of coherent light are highly perturbed by interaction with microstructural changes in pre-malignant tissue, holding promise for label-free early cancer detec…

physics.bio-ph2018★ 67 cited

Theory of mechano-chemical patterning in biphasic biological tissues

P. Recho, A. Hallou, E. Hannezo

The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. H…

q-bio.QM2018★ 35 cited

Refractive index measurements of single, spherical cells using digital holographic microscopy

Mirjam Schürmann, Jana Scholze, Paul Müller +4

In this chapter, we introduce digital holographic microscopy (DHM) as a marker-free method to determine the refractive index of single, spherical cells in suspension. The refractiv…

math.NA2018★ 17 cited

Reconstruction of optical vector-fields with applications in endoscopic imaging

Milana Gataric, George S. D. Gordon, Francesco Renna +3

We introduce a framework for the reconstruction of the amplitude, phase and polarisation of an optical vector-field using calibration measurements acquired by an imaging device wit…

q-bio.TO2017★ 3 cited

Extreme value statistics of mutation accumulation in renewing cell populations

Philip Greulich, Benjamin D. Simons

The emergence of a predominant phenotype within a cell population is often triggered by a rare accumulation of DNA mutations in a single cell. For example, tumors may be initiated…

q-bio.GN2014★ 18 cited

VSEAMS: A pipeline for variant set enrichment analysis using summary GWAS data identifies IKZF3, BATF and ESRRA as key transcription factors in type 1 diabetes

Oliver S Burren, Hui Guo, Chris Wallace

Motivation: Genome-wide association studies (GWAS) have identified many loci implicated in disease susceptibility. Integration of GWAS summary statistics (p values) and functional…