167 citations · 390 across the 11 of their papers we have counts for
11 papers
Beads, springs and fields: particle-based vs continuum models in cell biophysics
Valerio Sorichetti, Juraj Májek, Ivan Palaia +4
Quantitative modeling has become an essential tool in modern biophysics, driven by advances in both experimental techniques and theoretical frameworks. Powerful high-resolution tec…
Emergent dynamics of active elastic microbeams
Q. Martinet, Y. Li, A. Aubret +2
In equilibrium, the physical properties of matter are set by the interactions between the constituents. In contrast, the energy input of the individual components controls the beha…
Mechanochemical bistability of intestinal organoids enables robust morphogenesis
Shi-Lei Xue, Qiutan Yang, Prisca Liberali +1
How pattern and form are generated in a reproducible manner during embryogenesis remains poorly understood. Intestinal organoid morphogenesis involves a number of mechanochemical r…
Mechanically-driven Stem Cell Separation in Tissues caused by Proliferating Daughter Cells
Johannes C. Krämer, Edouard Hannezo, Gerhard Gompper +1
The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be ti…
Geometry adaptation of protrusion and polarity dynamics in confined cell migration
David B. Brückner, Matthew Schmitt, Alexandra Fink +6
Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and t…
Stem cell lineage survival as a noisy competition for niche access
Bernat Corominas-Murtra, Colinda L. G. J. Scheele, Kasumi Kishi +4
Understanding to what extent stem cell potential is a cell-intrinsic property, or an emergent behavior coming from global tissue dynamics and geometry, is a key outstanding questio…
Theory of mechano-chemical patterning in biphasic biological tissues
P. Recho, A. Hallou, E. Hannezo
The formation of self-organized patterns is key to the morphogenesis of multicellular organisms, although a comprehensive theory of biological pattern formation is still lacking. H…
Theory of epithelial cell shape transitions induced by mechanoactive chemical gradients
Kinjal Dasbiswas, Edouard Hannezo, Nir. S. Gov
Cell shape is determined by a balance of intrinsic properties of the cell as well as its mechanochemical environment. Inhomogeneous shape changes underly many morphogenetic events…
An interplay of migratory and division forces as a generic mechanism for stem cell patterns
Edouard Hannezo, Alice Coucke, Jean-François Joanny
In many adult tissues, stem cells and differentiated cells are not homogeneously distributed : stem cells are arranged in periodic "niches", and differentiated cells are constantly…
Mechanical Instabilities of Biological Tubes
Edouard Hannezo, Jean-Francois Joanny, Jacques Prost
We study theoretically the shapes of biological tubes affected by various pathologies. When epithelial cells grow at an uncontrolled rate, the negative tension produced by their di…
Instabilities of monolayered epithelia: shape and structure of villi and crypts
Edouard Hannezo, Jacques Prost, Jean-Francois Joanny
We study theoretically the shapes of a dividing epithelial monolayer of cells lying on top of an elastic stroma. The negative tension created by cell division provokes a buckling i…