445 citations
- University of California, Santa BarbaraUS6 papers
- Max Planck Institute for Intelligent SystemsDE5 papers
- Kavli Institute for Theoretical PhysicsUS4 papers
- Max Planck SocietyDE4 papers
- Karolinska InstitutetSE3 papers
- Karolinska University HospitalSE3 papers
- Stanford UniversityUS3 papers
- Centre National de la Recherche ScientifiqueFR2 papers
- Los Alamos National LaboratoryUS2 papers
- Stockholm South General HospitalSE2 papers
- University of CambridgeGB2 papers
- University of TübingenDE2 papers
9 papers · 1 filter
Adaptive nonparametric detection in cryo-electron microscopy
Mikhail Langovoy, Michael Habeck, Bernhard Schoelkopf
Cryo-electron microscopy (cryo-EM) is an emerging experimental method to characterize the structure of large biomolecular assemblies. Single particle cryo-EM records 2D images (so-…
The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana
Erik Wijnker, Geo Velikkakam James, Jia Ding +14
Knowledge of the exact distribution of meiotic crossovers (COs) and gene conversions (GCs) is essential for understanding many aspects of population genetics and evolution, from ha…
Spatial statistics, image analysis and percolation theory
Mikhail Langovoy, Michael Habeck, Bernhard Schölkopf
We develop a novel method for detection of signals and reconstruction of images in the presence of random noise. The method uses results from percolation theory. We specifically ad…
Inferring HIV escape rates from multi-locus genotype data
Taylor A. Kessinger, Alan S. Perelson, Richard A. Neher
Cytotoxic T-lymphocytes (CTLs) recognize viral protein fragments displayed by major histocompatibility complex (MHC) molecules on the surface of virally infected cells and generate…
Coalescence, genetic diversity in sexual populations under selection
Richard A. Neher, Taylor A. Kessinger, Boris I. Shraiman
In sexual populations, selection operates neither on the whole genome, which is repeatedly taken apart and reassembled by recombination, nor on individual alleles that are tightly…
The rise and fall of the Phytophthora infestans lineage that triggered the Irish potato famine
Kentaro Yoshida, Verena J. Schuenemann, Liliana M. Cano +10
Phytophthora infestans, the cause of potato late blight, is infamous for having triggered the Irish Great Famine in the 1840s. Until the late 1970s, P. infestans diversity outside…