output
19982026
most citedPopulation genomics of intrapatient HIV-1 evolution

282 citations

32 papers

cs.SD2026

From Black Box to Glass Box: Cross-Model ASR Disagreement to Prioto Review in Ambient AI Scribe Documentation

Abdolamir Karbalaie, Fernando Seoane, Farhad Abtahi

Ambient AI "scribe" systems promise to reduce clinical documentation burden, but automatic speech recognition (ASR) errors can remain unnoticed without careful review, and high-qua…

cs.CR2025★ 9 cited

Data Poisoning Vulnerabilities Across Healthcare AI Architectures: A Security Threat Analysis

Farhad Abtahi, Fernando Seoane, Iván Pau +1

Healthcare AI systems face major vulnerabilities to data poisoning that current defenses and regulations cannot adequately address. We analyzed eight attack scenarios in four categ…

cs.AI2025★ 4 cited

Leveraging Imperfection with MEDLEY A Multi-Model Approach Harnessing Bias in Medical AI

Farhad Abtahi, Mehdi Astaraki, Fernando Seoane

Bias in medical artificial intelligence is conventionally viewed as a defect requiring elimination. However, human reasoning inherently incorporates biases shaped by education, cul…

cs.AI2025★ 2 cited

HealthProcessAI: A Technical Framework and Proof-of-Concept for LLM-Enhanced Healthcare Process Mining

Eduardo Illueca-Fernandez, Kaile Chen, Fernando Seoane +1

Process mining has emerged as a powerful analytical technique for understanding complex healthcare workflows. However, its application faces significant barriers, including technic…

eess.IV2025

Potential and challenges of generative adversarial networks for super-resolution in 4D Flow MRI

Oliver Welin Odeback, Arivazhagan Geetha Balasubramanian, Jonas Schollenberger +9

4D Flow Magnetic Resonance Imaging (4D Flow MRI) enables non-invasive quantification of blood flow and hemodynamic parameters. However, its clinical application is limited by low s…

cs.CV2025★ 3 cited

Synthesizing Individualized Aging Brains in Health and Disease with Generative Models and Parallel Transport

Jingru Fu, Yuqi Zheng, Neel Dey +2

Simulating prospective magnetic resonance imaging (MRI) scans from a given individual brain image is challenging, as it requires accounting for canonical changes in aging and/or di…

cs.CV2024★ 4 cited

Pediatric brain tumor classification using digital histopathology and deep learning: evaluation of SOTA methods on a multi-center Swedish cohort

Iulian Emil Tampu, Per Nyman, Christoforos Spyretos +7

Brain tumors are the most common solid tumors in children and young adults, but the scarcity of large histopathology datasets has limited the application of computational pathology…

cs.CV2024★ 50 cited

A large-scale multicenter breast cancer DCE-MRI benchmark dataset with expert segmentations

Lidia Garrucho, Kaisar Kushibar, Claire-Anne Reidel +30

Artificial Intelligence (AI) research in breast cancer Magnetic Resonance Imaging (MRI) faces challenges due to limited expert-labeled segmentations. To address this, we present a…

q-bio.QM2023★ 17 cited

A graph neural network-based model with Out-of-Distribution Robustness for enhancing Antiretroviral Therapy Outcome Prediction for HIV-1

Giulia Di Teodoro, Federico Siciliano, Valerio Guarrasi +6

Predicting the outcome of antiretroviral therapies (ART) for HIV-1 is a pressing clinical challenge, especially when the ART includes drugs with limited effectiveness data. This sc…

cs.LG2023

Deep Learning for Time Series Classification of Parkinson's Disease Eye Tracking Data

Gonzalo Uribarri, Simon Ekman von Huth, Josefine Waldthaler +2

Eye-tracking is an accessible and non-invasive technology that provides information about a subject's motor and cognitive abilities. As such, it has proven to be a valuable resourc…

cs.LG2023★ 6 cited

Incorporating temporal dynamics of mutations to enhance the prediction capability of antiretroviral therapy's outcome for HIV-1

Giulia Di Teodoro, Martin Pirkl, Francesca Incardona +6

Motivation: In predicting HIV therapy outcomes, a critical clinical question is whether using historical information can enhance predictive capabilities compared with current or la…

eess.IV2023★ 23 cited

The ACROBAT 2022 Challenge: Automatic Registration Of Breast Cancer Tissue

Philippe Weitz, Masi Valkonen, Leslie Solorzano +38

The alignment of tissue between histopathological whole-slide-images (WSI) is crucial for research and clinical applications. Advances in computing, deep learning, and availability…

eess.IV2022★ 34 cited

High-resolution synthesis of high-density breast mammograms: Application to improved fairness in deep learning based mass detection

Lidia Garrucho, Kaisar Kushibar, Richard Osuala +7

Computer-aided detection systems based on deep learning have shown good performance in breast cancer detection. However, high-density breasts show poorer detection performance sinc…

q-bio.BM2022★ 28 cited

NMR spectrum reconstruction as a pattern recognition problem

Amir Jahangiri, Xiao Han, Dmitry Lesovoy +4

A new deep neural network based on the WaveNet architecture (WNN) is presented, which is designed to grasp specific patterns in the NMR spectra. When trained at a fixed non-uniform…

eess.IV2022★ 11 cited

Generative Aging of Brain Images with Diffeomorphic Registration

Jingru Fu, Antonios Tzortzakakis, José Barroso +3

Analyzing and predicting brain aging is essential for early prognosis and accurate diagnosis of cognitive diseases. The technique of neuroimaging, such as Magnetic Resonance Imagin…

cs.CV2021★ 31 cited

Transcriptome-wide prediction of prostate cancer gene expression from histopathology images using co-expression based convolutional neural networks

Philippe Weitz, Yinxi Wang, Kimmo Kartasalo +5

Molecular phenotyping by gene expression profiling is common in contemporary cancer research and in molecular diagnostics. However, molecular profiling remains costly and resource…

eess.IV2020★ 36 cited

CG-SENSE revisited: Results from the first ISMRM reproducibility challenge

Oliver Maier, Steven H. Baete, Alexander Fyrdahl +11

Purpose: The aim of this work is to shed light on the issue of reproducibility in MR image reconstruction in the context of a challenge. Participants had to recreate the results of…

physics.med-ph2019★ 179 cited

The reliability of a deep learning model in clinical out-of-distribution MRI data: a multicohort study

Gustav Mårtensson, Daniel Ferreira, Tobias Granberg +22

Deep learning (DL) methods have in recent years yielded impressive results in medical imaging, with the potential to function as clinical aid to radiologists. However, DL models in…

eess.IV2019★ 25 cited

A Deep Learning based Pipeline for Efficient Oral Cancer Screening on Whole Slide Images

Jiahao Lu, Nataša Sladoje, Christina Runow Stark +3

Oral cancer incidence is rapidly increasing worldwide. The most important determinant factor in cancer survival is early diagnosis. To facilitate large scale screening, we propose…

q-bio.NC2019★ 108 cited

Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons

Alex Bersellini Farinotti, Gustaf Wigerblad, Diana Nascimento +28

Rheumatoid arthritis-associated joint pain is frequently observed independent of disease activity, suggesting unidentified pain mechanisms. We demonstrate that antibodies binding t…

cs.CV2019★ 1 cited

US-net for robust and efficient nuclei instance segmentation

Zhaoyang Xu, Faranak Sobhani, Carlos Fernandez Moro +1

We present a novel neural network architecture, US-Net, for robust nuclei instance segmentation in histopathology images. The proposed framework integrates the nuclei detection and…

physics.med-ph2018★ 32 cited

AVRA: Automatic Visual Ratings of Atrophy from MRI images using Recurrent Convolutional Neural Networks

Gustav Mårtensson, Daniel Ferreira, Lena Cavallin +4

Quantifying the degree of atrophy is done clinically by neuroradiologists following established visual rating scales. For these assessments to be reliable the rater requires substa…

q-bio.BM2018★ 47 cited

Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection

Katy A. Lloyd, Johanna Steen, Khaled Amara +15

Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) m…

q-bio.BM2017★ 30 cited

Depressed serum IgM levels in SLE are restricted to defined subgroups

Caroline Gronwall, Uta Hardt, Johanna T. Gustafsson +9

Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE)…