67 citations · 97 across the 2 of their papers we have counts for
3 papers
Variable domain N-linked glycosylation and negative surface charge are key features of monoclonal ACPA: implications for B-cell selection
Katy A. Lloyd, Johanna Steen, Khaled Amara +15
Autoreactive B cells have a central role in the pathogenesis of rheumatoid arthritis (RA), and recent findings have proposed that anti-citrullinated protein autoantibodies (ACPA) m…
Depressed serum IgM levels in SLE are restricted to defined subgroups
Caroline Gronwall, Uta Hardt, Johanna T. Gustafsson +9
Natural IgM autoantibodies have been proposed to convey protection from autoimmune pathogenesis. Herein, we investigated the IgM responses in 396 systemic lupus erythematosus (SLE)…
Autoreactivity to malondialdehyde-modifications in rheumatoid arthritis is linked to disease activity and synovial pathogenesis
Caroline Gronwall, Khaled Amara, Uta Hardt +12
Oxidation-associated malondialdehyde (MDA) modification of proteins can generate immunogenic neo-epitopes that are recognized by autoantibodies. In health, IgM antibodies to MDA-ad…