278 citations
- Erasmus MCNL1 paper
- Gentofte HospitalDK1 paper
- Max Planck Institute for Dynamics and Self-OrganizationDE1 paper
- Max Planck Institute for Intelligent SystemsDE1 paper
- Max Planck SocietyDE1 paper
- RigshospitaletDK1 paper
- Stanford UniversityUS1 paper
- University of California, Santa BarbaraUS1 paper
- University of CopenhagenDK1 paper
5 papers
Geometric tree kernels: Classification of COPD from airway tree geometry
Aasa Feragen, Jens Petersen, Dominik Grimm +4
Methodological contributions: This paper introduces a family of kernels for analyzing (anatomical) trees endowed with vector valued measurements made along the tree. While state-of…
Genealogies of rapidly adapting populations
Richard A. Neher, Oskar Hallatschek
The genetic diversity of a species is shaped by its recent evolutionary history and can be used to infer demographic events or selective sweeps. Most inference methods are based on…
FFPopSim: An efficient forward simulation package for the evolution of large populations
Fabio Zanini, Richard A. Neher
The analysis of the evolutionary dynamics of a population with many polymorphic loci is challenging since a large number of possible genotypes needs to be tracked. In the absence o…
Fluctuations of fitness distributions and the rate of Muller's ratchet
Richard A. Neher, Boris I. Shraiman
The accumulation of deleterious mutations is driven by rare fluctuations which lead to the loss of all mutation free individuals, a process known as Muller's ratchet. Even though M…
Estimating the Strength of Selective Sweeps from Deep Population Diversity Data
Philipp W. Messer, Richard A. Neher
Selective sweeps are typically associated with a local reduction of genetic diversity around the adaptive site. However, selective sweeps can also quickly carry neutral mutations t…