activity
19942021
most citedDirect-coupling analysis of residue co-evolution captures native contacts across many protein families

1.6k citations · 5.6k across the 43 of their papers we have counts for

collaborators

43 papers

q-bio.PE2021★ 54 cited

A Traveling-Wave Solution for Bacterial Chemotaxis with Growth

Avaneesh V. Narla, Jonas Cremer, Terry Hwa

Bacterial cells navigate around their environment by directing their movement along chemical gradients. This process, known as chemotaxis, can promote the rapid expansion of bacter…

q-bio.MN2016★ 193 cited

Constrained Allocation Flux Balance Analysis

Matteo Mori, Terence Hwa, Olivier C. Martin +2

New experimental results on bacterial growth inspire a novel top-down approach to study cell metabolism, combining mass balance and proteomic constraints to extend and complement F…

cond-mat.soft2012★ 197 cited

Stripe formation in bacterial systems with density-suppressed motility

Xiongfei Fu, Lei-Han Tang, Chenli Liu +3

Engineered bacteria in which motility is reduced by local cell density generate periodic stripes of high and low density when spotted on agar plates. We study theoretically the ori…

q-bio.QM2011★ 1.6k cited

Direct-coupling analysis of residue co-evolution captures native contacts across many protein families

Faruck Morcos, Andrea Pagnani, Bryan Lunt +7

The similarity in the three-dimensional structures of homologous proteins imposes strong constraints on their sequence variability. It has long been suggested that the resulting co…

q-bio.MN2011★ 101 cited

Dissecting the Specificity of Protein-Protein Interaction in Bacterial Two-Component Signaling: Orphans and Crosstalks

Andrea Procaccini, Bryan Lunt, Hendrik Szurmant +2

Predictive understanding of the myriads of signal transduction pathways in a cell is an outstanding challenge of systems biology. Such pathways are primarily mediated by specific b…

q-bio.BM2009★ 1.1k cited

Identification of direct residue contacts in protein-protein interaction by message passing

M. Weigt, R. A. White, H. Szurmant +2

Understanding the molecular determinants of specificity in protein-protein interaction is an outstanding challenge of postgenome biology. The availability of large protein database…