Analytical study of the effect of recombination on evolution via DNA shuffling
arXiv:physics/0303120 · doi:10.1103/PhysRevE.69.051911
Abstract
We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selection, recombination and point mutations. The simplicity of the model allows us to obtain a full analytical treatment of both its dynamical and equilibrium properties, for the case of an infinite population. We also briefly discuss finite population size corrections.