29 citations · 36 across the 3 of their papers we have counts for
3 papers
q-bio.GN2013
H3K4 mono- and di-methyltransferase MLL4 is required for enhancer activation during cell differentiation
Ji-Eun Lee, Chaochen Wang, Shiliyang Xu +7
Enhancers play a central role in cell-type-specific gene expression and are marked by H3K4me1/2. Active enhancers are further marked by H3K27ac. However, the methyltransferases res…
physics.bio-ph2003★ 7 cited
Analytical study of the effect of recombination on evolution via DNA shuffling
Weiqun Peng, Herbert Levine, Terence Hwa +1
We investigate a multi-locus evolutionary model which is based on the DNA shuffling protocol widely applied in \textit{in vitro} directed evolution. This model incorporates selecti…
cond-mat.stat-mech2002★ 29 cited
Dynamics of Competitive Evolution on a Smooth Landscape
Weiqun Peng, Ulrich Gerland, Terence Hwa +1
We study competitive DNA sequence evolution directed by {\it in vitro} protein binding. The steady-state dynamics of this process is well described by a shape-preserving pulse whic…