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Quantitative Characterization of Combinatorial Transcriptional Control of the Lactose Operon of E. coli
T. E. Kuhlman, Z. Zhang, M. H. Saier +1
It is the goal of systems biology to understand the behavior of the whole in terms of the knowledge of the parts. This is hard to achieve in many cases due to the difficulty of cha…
Transcriptional Regulation by the Numbers 2: Applications
Lacramioara Bintu, Nicolas E. Buchler, Hernan G. Garcia +5
With the increasing amount of experimental data on gene expression and regulation, there is a growing need for quantitative models to describe the data and relate them to the diffe…
Transcriptional Regulation by the Numbers 1: Models
Lacramioara Bintu, Nicolas E. Buchler, Hernan G. Garcia +4
The study of gene regulation and expression is often discussed in quantitative terms. In particular, the expression of genes is regularly characterized with respect to how much, ho…