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Stripe formation in bacterial systems with density-suppressed motility
Xiongfei Fu, Lei-Han Tang, Chenli Liu +3
Engineered bacteria in which motility is reduced by local cell density generate periodic stripes of high and low density when spotted on agar plates. We study theoretically the ori…
Translocation of structured polynucleotides through nanopores
Ulrich Gerland, Ralf Bundschuh, Terence Hwa
We investigate theoretically the translocation of structured RNA/DNA molecules through narrow pores which allow single but not double strands to pass. The unzipping of basepaired r…
The style of genetic computing
Nicolas E. Buchler, Ulrich Gerland, Terence Hwa
Cells receive a wide variety of cellular and environmental signals, which must be processed combinatorially to generate specific and timely genetic responses. We present here a the…
Mechanically probing the folding pathway of single RNA molecules
Ulrich Gerland, Ralf Bundschuh, Terence Hwa
We study theoretically the denaturation of single RNA molecules by mechanical stretching, focusing on signatures of the (un)folding pathway in molecular fluctuations. Our model des…
Force-induced denaturation of RNA
Ulrich Gerland, Ralf Bundschuh, Terence Hwa
We describe quantitatively a RNA molecule under the influence of an external force exerted at its two ends as in a typical single-molecule experiment. Our calculation incorporates…
Hydrodynamics of the Kuramoto-Sivashinsky Equation in Two Dimensions
Bruce Boghosian, Carson C. Chow, Terence Hwa
The large scale properties of spatiotemporal chaos in the 2d Kuramoto-Sivashinsky equation are studied using an explicit coarse graining scheme. A set of intermediate equations are…
Polymer Reptation in Disordered Media
D. Cule, T. Hwa
The effect of ambient disorders and sequence heterogeneities on the reptation of a long polymer is studied with the aid of a disordered tube model. The dynamics of a random heterop…