2 citations · 4 across the 7 of their papers we have counts for
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Evolutionary conservation of the folding nucleus
Leonid Mirny, Eugene Shakhnovich
In this Communication we present statistical analysis of conservation profiles in families of homologous sequences for nine proteins whose folding nucleus was determined by protein…
The Folding Thermodynamics and Kinetics of Crambin Using an All-Atom Monte Carlo Simulation
J. Shimada, E. L. Kussell, E. I. Shakhnovich
We present a novel Monte Carlo simulation of protein folding, in which all heavy atoms are represented as interacting hard spheres. This model includes all degrees of freedom relev…
Understanding conserved amino acids in proteins
Nikolay V. Dokholyan, Leonid A. Mirny, Eugene I. Shakhnovich
It has been conjectured that evolution exerted pressure to preserve amino acids bearing thermodynamic, kinetic, and functional roles. In this letter we show that the physical requi…