output
20032026
most citedGPU-based Low Dose CT Reconstruction via Edge-preserving Total Variation Regularization

399 citations

Showing 2023Show all

16 papers · 1 filter

physics.med-ph2023

Dosimetric calibration of an anatomically specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments

Jinghui Wang, Stavros Melemenidis, Rakesh Manjappa +16

We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiolog…

physics.med-ph2023

Dynamic CBCT Imaging using Prior Model-Free Spatiotemporal Implicit Neural Representation (PMF-STINR)

Hua-Chieh Shao, Mengke Tielige, Tinsu Pan +1

Dynamic cone-beam computed tomography (CBCT) can capture high-spatial-resolution, time-varying images for motion monitoring, patient setup, and adaptive planning of radiotherapy. H…

stat.ME2023★ 2 cited

A reluctant additive model framework for interpretable nonlinear individualized treatment rules

Jacob M. Maronge, Jared D. Huling, Guanhua Chen

Individualized treatment rules (ITRs) for treatment recommendation is an important topic for precision medicine as not all beneficial treatments work well for all individuals. Inte…

cs.CV2023★ 19 cited

Feature Extraction for Generative Medical Imaging Evaluation: New Evidence Against an Evolving Trend

McKell Woodland, Austin Castelo, Mais Al Taie +8

Fréchet Inception Distance (FID) is a widely used metric for assessing synthetic image quality. It relies on an ImageNet-based feature extractor, making its applicability to medica…

q-bio.OT2023★ 24 cited

Forum on immune digital twins: a meeting report

Reinhard Laubenbacher, Fred Adler, Gary An +16

Medical digital twins are computational models of human biology relevant to a given medical condition, which can be tailored to an individual patient, thereby predicting the course…

physics.med-ph2023★ 7 cited

Evolving Horizons in Radiotherapy Auto-Contouring: Distilling Insights, Embracing Data-Centric Frameworks, and Moving Beyond Geometric Quantification

Kareem A. Wahid, Carlos E. Cardenas, Barbara Marquez +8

Deep learning has significantly advanced the potential for automated contouring in radiotherapy planning. In this manuscript, guided by contemporary literature, we underscore three…

q-bio.GN2023★ 3 cited

Multi-View Variational Autoencoder for Missing Value Imputation in Untargeted Metabolomics

Chen Zhao, Kuan-Jui Su, Chong Wu +13

Background: Missing data is a common challenge in mass spectrometry-based metabolomics, which can lead to biased and incomplete analyses. The integration of whole-genome sequencing…

stat.ME2023★ 1 cited

Separable effects for adherence

Kerollos Nashat Wanis, Mats Julius Stensrud, Aaron Leor Sarvet

Comparing different medications is complicated when adherence to these medications differs. We can overcome the adherence issue by assessing effectiveness under sustained use, as i…

cs.CL2023★ 7 cited

Text Classification of Cancer Clinical Trial Eligibility Criteria

Yumeng Yang, Soumya Jayaraj, Ethan B Ludmir +1

Automatic identification of clinical trials for which a patient is eligible is complicated by the fact that trial eligibility is stated in natural language. A potential solution to…

physics.med-ph2023★ 58 cited

Current Methods for Hyperpolarized [1-13C]pyruvate MRI Human Studies

Peder EZ Larson, Jenna ML Bernard, James A Bankson +16

MRI with hyperpolarized (HP) 13C agents, also known as HP 13C MRI, can measure processes such as localized metabolism that is altered in numerous cancers, liver, heart, kidney dise…

cs.CE2023★ 100 cited

Predictive Digital Twin for Optimizing Patient-Specific Radiotherapy Regimens under Uncertainty in High-Grade Gliomas

Anirban Chaudhuri, Graham Pash, David A. Hormuth +6

We develop a methodology to create data-driven predictive digital twins for optimal risk-aware clinical decision-making. We illustrate the methodology as an enabler for an anticipa…

cs.LG2023★ 4 cited

Dimensionality Reduction for Improving Out-of-Distribution Detection in Medical Image Segmentation

McKell Woodland, Nihil Patel, Mais Al Taie +4

Clinically deployed segmentation models are known to fail on data outside of their training distribution. As these models perform well on most cases, it is imperative to detect out…

eess.IV2023★ 19 cited

Zero-DeepSub: Zero-Shot Deep Subspace Reconstruction for Rapid Multiparametric Quantitative MRI Using 3D-QALAS

Yohan Jun, Yamin Arefeen, Jaejin Cho +7

Purpose: To develop and evaluate methods for 1) reconstructing 3D-quantification using an interleaved Look-Locker acquisition sequence with T2 preparation pulse (3D-QALAS) time-ser…

stat.ME2023

Overlapping Indices for Dynamic Information Borrowing in Bayesian Hierarchical Modeling

Xuetao Lu, J. Jack Lee

Bayesian hierarchical model (BHM) has been widely used in synthesizing information across subgroups. Identifying heterogeneity in the data and determining proper strength of borrow…

q-bio.OT2023★ 87 cited

Community-developed checklists for publishing images and image analysis

Christopher Schmied, Michael Nelson, Sergiy Avilov +51

Images document scientific discoveries and are prevalent in modern biomedical research. Microscopy imaging in particular is currently undergoing rapid technological advancements. H…

cs.CV2023★ 1 cited

Deep Learning Provides Rapid Screen for Breast Cancer Metastasis with Sentinel Lymph Nodes

Kareem Allam, Xiaohong Iris Wang, Songlin Zhang +6

Deep learning has been shown to be useful to detect breast cancer metastases by analyzing whole slide images of sentinel lymph nodes. However, it requires extensive scanning and an…