output
20032026
most citedGPU-based Low Dose CT Reconstruction via Edge-preserving Total Variation Regularization

399 citations

Showing 2019Show all

11 papers · 1 filter

stat.ME2019★ 16 cited

RCRnorm: An integrated system of random-coefficient hierarchical regression models for normalizing NanoString nCounter data

Gaoxiang Jia, Xinlei Wang, Qiwei Li +4

Formalin-fixed paraffin-embedded (FFPE) samples have great potential for biomarker discovery, retrospective studies and diagnosis or prognosis of diseases. Their application, howev…

physics.med-ph2019★ 27 cited

Dosimetric performance of a multi-point plastic scintillator dosimeter as a tool for real-time source tracking in high dose rate brachytherapy

Haydee M. Linares Rosales, Louis Archambault, Sam Beddar +1

Purpose: To present the performance of a multi-point plastic scintillation detector (mPSD) as a tool in vivo dosimetry in brachytherapy. Methods: A previously optimized three-point…

stat.ME2019★ 11 cited

Bayesian Inference of Networks Across Multiple Sample Groups and Data Types

Elin Shaddox, Christine B. Peterson, Francesco C. Stingo +5

In this paper, we develop a graphical modeling framework for the inference of networks across multiple sample groups and data types. In medical studies, this setting arises wheneve…

stat.ME2019

Estimating the Optimal Linear Combination of Biomarkers using Spherically Constrained Optimization

Priyam Das, Debsurya De, Raju Maiti +5

In the context of a binary classification problem, the optimal linear combination of continuous predictors can be estimated by maximizing an empirical estimate of the area under th…

stat.ME2019★ 1 cited

Bayesian Modeling of Multiple Structural Connectivity Networks During the Progression of Alzheimer's Disease

Christine B. Peterson, Nathan Osborne, Francesco C. Stingo +3

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression usin…

physics.med-ph2019★ 39 cited

Cohort-based T-SSIM Visual Computing for Radiation Therapy Prediction and Exploration

A. Wentzel, P. Hanula, T. Luciani +6

We describe a visual computing approach to radiation therapy (RT) planning, based on spatial similarity within a patient cohort. In radiotherapy for head and neck cancer treatment,…

q-bio.QM2019

Dynamic Prediction of Competing Risk Events using Landmark Sub-distribution Hazard Model with Multiple Longitudinal Biomarker

Cai Wu, Liang Li, Ruosha Li

The cause-specific cumulative incidence function (CIF) quantifies the subject-specific disease risk with competing risk outcome. With longitudinally collected biomarker data, it is…

q-bio.GN2019

Genome analysis and pleiotropy assessment using causal networks with loss of function mutation and metabolomics

Azam Yazdani, Akram Yazdani, Sarah H. Elsea +4

Background: Many genome-wide association studies have detected genomic regions associated with traits, yet understanding the functional causes of association often remains elusive.…

physics.ins-det2019★ 11 cited

A Scintillator Attenuation Spectrometer For Intense Gamma-Rays

Edison Liang, Kevin Qinyuan Zheng, Kelly Yao +10

A new type of compact high resolution high sensitivity gamma ray spectrometer for short pulse intense 250 keV to 50 MeV gamma rays has been developed by combining the principles of…

physics.med-ph2019★ 14 cited

Renormalization of radiobiological response functions by energy loss fluctuations and complexities in chromosome aberration induction: deactivation theory for proton therapy from cells to tumor control

Ramin Abolfath, Yusuf Helo, Lawrence Bronk +3

We employ a multi-scale mechanistic approach to investigate radiation induced cell toxicities and deactivation mechanisms as a function of linear energy transfer in hadron therapy.…

stat.ML2019★ 70 cited

Sensitivity Analysis of Deep Neural Networks

Hai Shu, Hongtu Zhu

Deep neural networks (DNNs) have achieved superior performance in various prediction tasks, but can be very vulnerable to adversarial examples or perturbations. Therefore, it is cr…