105 citations · 242 across the 10 of their papers we have counts for
10 papers
Differential tissue sparing of FLASH ultra high dose rates: an {\it in-silico} study
Ramin Abolfath, Alexander Baikalov, Sohrab Rahvar +4
Purpose: To propose a theory for the differential tissue sparing of FLASH ultra high dose rates (UHDR) through inter-track reaction-diffusion mechanism. Methods: We calculate the t…
Modeling interspur interactions as a potential mechanism of the FLASH effect
Alexander Baikalov, Ramin Abolfath, Radhe Mohan +3
The mechanism responsible for the FLASH effect, normal tissue sparing by ultra-high dose rate (UHDR) irradiation with isoeffective tumor control compared to conventional dose rate…
The effect of non-ionizing excitations on the diffusion of ion species and inter-track correlations in FLASH ultra-high dose rate radiotherapy
Ramin Abolfath, Alexander Baikalov, Stefan Bartzsch +2
We present a microscopic mechanism that accounts for the outward burst of "cold" ion species (IS) in a high-energy particle track due to coupling with ''hot" non-ion species (NIS).…
Optimization of FLASH Proton Beams Using a Track-Repeating Algorithm
Qianxia Wang, Uwe Titt, Radhe Mohan +4
Methods: A phase space file in a plane at 202 mm downstream of the beam exit window is generated through tuning parameters to match FDC results with measured or MCNPX Monte Carlo-s…
Oxygen depletion in FLASH ultra-high-dose-rate radiotherapy: A molecular dynamics simulation
Ramin Abolfath, David Grosshans, Radhe Mohan
We present a first-principles molecular dynamics (MD) simulation and expound upon a mechanism of oxygen depletion hypothesis to explain the mitigation of normal tissue injury obser…
A New Approach to Modeling the Microdosimetry of Proton Therapy Beams
Ramin Abolfath, Yusuf Helo, David J. Carlson +3
{\bf Introduction}: To revisit the formulation of the mean chord length in microdosimetry and replace it by the particle mean free path appropriate for modelings in radio-biology.…