activity
20052026
most citedOxygen depletion in FLASH ultra-high-dose-rate radiotherapy: A molecular dynamics simulation

82 citations · 454 across the 30 of their papers we have counts for

collaborators

30 papers

physics.med-ph2026

Fractal geometry-governed oxygen diffusion: Tumors vs. Normal Tissues

Neda Valizadeh, Robabeh Rahimi, Ramin Abolfath

{\bf Purpose}: To develop a geometry-governed diffusion framework that explains differential tissue response under FLASH ultra-high dose rate (UHDR) irradiation by explicitly accou…

physics.med-ph2024★ 3 cited

A molecular dynamics simulation of the abrupt changes in the thermodynamic properties of water after formation of nano-bubbles / nano-cavities induced by passage of charged particles

Ramin Abolfath, Niayesh Afshordi, Sohrab Rahvar +6

We present a multi-scale formalism that accounts for the formation of nano-scale bubbles/cavities owing to a burst of water molecules after the passage of high energy charged parti…

physics.med-ph2024★ 2 cited

A Monte Carlo simulation framework for investigating the effect of inter-track coupling on HO productions at ultra-high dose rates

Ramin Abolfath, Sedigheh Fardirad, Houda Kacem +2

Background: Lower production of HO in water is a hallmark of ultra-high dose rate (UHDR) compared to the conventional dose rate (CDR). However, the current computational mo…

physics.med-ph2022

Differential tissue sparing of FLASH ultra high dose rates: an {\it in-silico} study

Ramin Abolfath, Alexander Baikalov, Sohrab Rahvar +4

Purpose: To propose a theory for the differential tissue sparing of FLASH ultra high dose rates (UHDR) through inter-track reaction-diffusion mechanism. Methods: We calculate the t…

physics.med-ph2022★ 3 cited

Modeling interspur interactions as a potential mechanism of the FLASH effect

Alexander Baikalov, Ramin Abolfath, Radhe Mohan +3

The mechanism responsible for the FLASH effect, normal tissue sparing by ultra-high dose rate (UHDR) irradiation with isoeffective tumor control compared to conventional dose rate…

physics.bio-ph2022★ 3 cited

Towards the Ionizing Radiation Induced Bond Dissociation Mechanism in Oxygen, Water, Guanine and DNA Fragmentation: A Density Functional Theory Simulation

Santosh KC, Ramin Abolfath

The radiation-induced damages in bio-molecules are ubiquitous processes in radiotherapy, radio-biology and critical to space-projects. In this study we present a precise quantifica…