output
20032026
most citedGPU-based Low Dose CT Reconstruction via Edge-preserving Total Variation Regularization

399 citations

Showing q-bio.QMShow all

9 papers · 1 filter

q-bio.QM2025

Foundation Models in Biomedical Imaging: Turning Hype into Reality

Amgad Muneer, Kai Zhang, Ibraheem Hamdi +6

Foundation models (FMs) are driving a prominent shift in biomedical imaging from task-specific models to unified backbone models for diverse tasks. This opens an avenue to integrat…

q-bio.QM2025

The Next Layer: Augmenting Foundation Models with Structure-Preserving and Attention-Guided Learning for Local Patches to Global Context Awareness in Computational Pathology

Muhammad Waqas, Rukhmini Bandyopadhyay, Eman Showkatian +12

Foundation models have recently emerged as powerful feature extractors in computational pathology, yet they typically omit mechanisms for leveraging the global spatial structure of…

q-bio.QM2025★ 16 cited

From Classical Machine Learning to Emerging Foundation Models: Review on Multimodal Data Integration for Cancer Research

Amgad Muneer, Muhammad Waqas, Maliazurina B Saad +16

Cancer research is increasingly driven by the integration of diverse data modalities, spanning from genomics and proteomics to imaging and clinical factors. However, extracting act…

q-bio.QM2024★ 2 cited

Assessing Engraftment Following Fecal Microbiota Transplant

Chloe Herman, Bridget M. Barker, Thais F. Bartelli +9

Fecal Microbiota Transplant (FMT) is an FDA approved treatment for recurrent Clostridium difficile infections, and is being explored for other clinical applications, from alleviati…

q-bio.QM2024

GENEVIC: GENetic data Exploration and Visualization via Intelligent interactive Console

Anindita Nath, Savannah Mwesigwa, Yulin Dai +2

Summary: The vast generation of genetic data poses a significant challenge in efficiently uncovering valuable knowledge. Introducing GENEVIC, an AI-driven chat framework that tackl…

q-bio.QM2021★ 2 cited

Hierarchical Phenotyping and Graph Modeling of Spatial Architecture in Lymphoid Neoplasms

Pingjun Chen, Muhammad Aminu, Siba El Hussein +2

The cells and their spatial patterns in the tumor microenvironment (TME) play a key role in tumor evolution, and yet the latter remains an understudied topic in computational patho…

q-bio.QM2020★ 1 cited

aPCoA: Covariate Adjusted Principal Coordinates Analysis

Yushu Shi, Liangliang Zhang, Kim-Anh Do +2

In fields such as ecology, microbiology, and genomics, non-Euclidean distances are widely applied to describe pairwise dissimilarity between samples. Given these pairwise distances…

q-bio.QM2019

Dynamic Prediction of Competing Risk Events using Landmark Sub-distribution Hazard Model with Multiple Longitudinal Biomarker

Cai Wu, Liang Li, Ruosha Li

The cause-specific cumulative incidence function (CIF) quantifies the subject-specific disease risk with competing risk outcome. With longitudinally collected biomarker data, it is…

q-bio.QM2016★ 110 cited

The limitations of model-based experimental design and parameter estimation in sloppy systems

Andrew White, Malachi Tolman, Howard D. Thames +3

We explore the relationship among model fidelity, experimental design, and parameter estimation in sloppy models. We show that the approximate nature of mathematical models poses c…