output
20022022
most citedWhy highly expressed proteins evolve slowly

883 citations

31 papers

physics.bio-ph2022★ 5 cited

Mathematical Modeling of Microscale Biology: Ion Pairing, Dielectric Decrement, and Born Energy in Glycosaminoglycan Brushes

William Ceely, Marina Chugunova, Ali Nadim +1

Biological macromolecules including nucleic acids, proteins, and glycosaminoglycans are typically anionic and can span domains of up to hundreds of nanometers and even micron lengt…

q-bio.PE2018★ 1 cited

How costly punishment, diversity, and density of connectivity influence cooperation in a biological network

Ivan C. Ezeigbo

It has been an old unsolved puzzle to evolutionary theorists on which mechanisms would increase large-scale cooperation in human societies. Thus, how such mechanisms operate in a b…

hep-th2017★ 21 cited

Power-counting during single-field slow-roll inflation

Peter Adshead, C. P. Burgess, R. Holman +1

We elucidate the counting of the relevant small parameters in inflationary perturbation theory. Doing this allows for an explicit delineation of the domain of validity of the semi-…

q-bio.MN2013★ 17 cited

A genome wide dosage suppressor network reveals genetic robustness and a novel mechanism for Huntington's disease

B. Patra, Y. Kon, G. Yadav +17

Mutational robustness is the extent to which an organism has evolved to withstand the effects of deleterious mutations. We explored the extent of mutational robustness in the buddi…

q-bio.BM2011★ 3 cited

Robust monomer-distribution biosignatures in evolving digital biota

Evan D. Dorn, Christoph Adami

Because organisms synthesize component molecules at rates that reflect those molecules' adaptive utility, we expect a population of biota to leave a distinctive chemical signature…

q-bio.QM2011★ 26 cited

Information content of colored motifs in complex networks

Christoph Adami, Jifeng Qian, Matthew Rupp +1

We study complex networks in which the nodes of the network are tagged with different colors depending on the functionality of the nodes (colored graphs), using information theory…