883 citations · 2.2k across the 5 of their papers we have counts for
4 papers
Why highly expressed proteins evolve slowly
D. Allan Drummond, Jesse D. Bloom, Christoph Adami +2
Much recent work has explored molecular and population-genetic constraints on the rate of protein sequence evolution. The best predictor of evolutionary rate is expression level, f…
Thermodynamic Prediction of Protein Neutrality
Jesse D. Bloom, Jonathan J. Silberg, Claus O. Wilke +3
We present a simple theory that uses thermodynamic parameters to predict the probability that a protein retains the wildtype structure after one or more random amino acid substitut…
Ab Initio Modeling of Ecosystems with Artificial Life
C. Adami
Artificial Life provides the opportunity to study the emergence and evolution of simple ecosystems in real time. We give an overview of the advantages and limitations of such an ap…
A Simple Explanation for Taxon Abundance Patterns
Johan Chu, Chris Adami
For taxonomic levels higher than species, the abundance distributions of number of subtaxa per taxon tend to approximate power laws, but often show strong deviationns from such a l…