output
20042026
most citedStructure and dynamics of molecular networks: A novel paradigm of drug discovery. A comprehensive review

916 citations

Showing 2013Show all

5 papers · 1 filter

q-bio.MN2013★ 66 cited

Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential mechanism

Peter Csermely, Janos Hodsagi, Tamas Korcsmaros +7

Cancer is increasingly perceived as a systems-level, network phenomenon. The major trend of malignant transformation can be described as a two-phase process, where an initial incre…

physics.med-ph2013

Rotating-crystal Malaria Diagnosis: Pre-clinical validation

Agnes Orban, Adam Butykai, Zsofia Prohle +8

Improving the efficiency of malaria diagnosis is one of the main goals of current malaria research. We have recently developed a magneto-optical (MO) method which allows high-sensi…

q-bio.MN2013★ 47 cited

Adaptation and learning of molecular networks as a description of cancer development at the systems-level: Potential use in anti-cancer therapies

David M. Gyurko, Daniel V. Veres, Dezso Modos +3

There is a widening recognition that cancer cells are products of complex developmental processes. Carcinogenesis and metastasis formation are increasingly described as systems-lev…

q-bio.MN2013★ 28 cited

Perturbation centrality and Turbine: a novel centrality measure obtained using a versatile network dynamics tool

Kristof Z. Szalay, Peter Csermely

Analysis of network dynamics became a focal point to understand and predict changes of complex systems. Here we introduce Turbine, a generic framework enabling fast simulation of a…

q-bio.MN2013★ 24 cited

Nodes having a major influence to break cooperation define a novel centrality measure: game centrality

Gabor I. Simko, Peter Csermely

Cooperation played a significant role in the self-organization and evolution of living organisms. Both network topology and the initial position of cooperators heavily affect the c…