198 citations
- Freie Universität BerlinDE5 papers
- Max Planck SocietyDE4 papers
- Vrije Universiteit AmsterdamNL4 papers
- Center for Theoretical Biological PhysicsUS3 papers
- University of CologneDE3 papers
- Centre National de la Recherche ScientifiqueFR2 papers
- Institute for Atomic and Molecular PhysicsNL2 papers
- Massachusetts Institute of TechnologyUS2 papers
- Mathématiques et Informatique Appliquées du Génome à l'EnvironnementFR2 papers
- Stanford UniversityUS2 papers
- University of California San DiegoUS2 papers
- University of GöttingenDE2 papers
4 papers · 1 filter
Universality of Long-Range Correlations in Expansion-Randomization Systems
Philipp W. Messer, Michael Lassig, Peter F. Arndt
We study the stochastic dynamics of sequences evolving by single site mutations, segmental duplications, deletions, and random insertions. These processes are relevant for the evol…
Substantial regional variation in substitution rates in the human genome: importance of GC content, gene density and telomere-specific effects
Peter F Arndt, Terence Hwa, Dmitri A Petrov
This study presents the first global, 1 Mbp level analysis of patterns of nucleotide substitutions along the human lineage. The study is based on the analysis of a large amount of…
Identification and Measurement of Neighbor Dependent Nucleotide Substitution Processes
Peter F. Arndt, Terence Hwa
The presence of neighbor dependencies generated a specific pattern of dinucleotide frequencies in all organisms. Especially, the CpG-methylation-deamination process is the predomin…
A Solvable Sequence Evolution Model and Genomic Correlations
Philipp W. Messer, Peter F. Arndt, Michael Lässig
We study a minimal model for genome evolution whose elementary processes are single site mutation, duplication and deletion of sequence regions and insertion of random segments. Th…