261 citations · 340 across the 8 of their papers we have counts for
8 papers
Molecular-scale, nonlinear actomyosin binding dynamics drive population-scale adaptation and evolutionary convergence
Jake McGrath, Colin Johnson, José Alvarado
Biological actuators -- from myosin motors to muscles -- follow Hill's model where a dimensionless parameter captures the nonlinear coupling between contraction rate and force…
Fluid Flow Induced Deformation of a Boundary Hair
Jonas P. Smucker, Zerrin M. Vural, José R. Alvarado +1
The deformation of a dense carpet of hair due to Stokes flow in a channel can be described by a nonlinear integro-differential equation for the shape of a single hair, which posses…
Uncovering the dynamic precursors to motor-driven contraction of active gels
Jose Alvarado, Luca Cipelletti, Gijsje Koenderink
Cells and tissues have the remarkable ability to actively generate the forces required to change their shape. This active mechanical behavior is largely mediated by the actin cytos…
Force percolation of contractile active gels
José Alvarado, Misha Sheinman, Abhinav Sharma +2
Cells and tissues exert forces and can actively change shape. This strikingly autonomous behavior is powered by the cytoskeleton, which includes an active gel of actin filaments, c…
Reply to Comment on "Anomalous Discontinuity at the Percolation Critical Point of Active Gels"
M. Sheinman, A. Sharma, F. C. MacKintosh
In this reply we discuss definition and estimation of the Fisher exponent in the no-enclaves percolation (NEP) model.
Active biopolymer networks generate scale-free but euclidean clusters
M. Sheinman, A. Sharma, J. Alvarado +2
We report analytical and numerical modelling of active elastic networks, motivated by experiments on crosslinked actin networks contracted by myosin motors. Within a broad range of…
Anomalous discontinuity at the percolation critical point of active gels
M. Sheinman, A. Sharma, J. Alvarado +2
We develop a percolation model motivated by recent experimental studies of gels with active network remodeling by molecular motors. This remodeling was found to lead to a critical…
Molecular motors robustly drive active gels to a critically connected state
Jose Alvarado, Michael Sheinman, Abhinav Sharma +2
Living systems often exhibit internal driving: active, molecular processes drive nonequilibrium phenomena such as metabolism or migration. Active gels constitute a fascinating clas…